A three-dimensional model with two-body interactions for endothelial cells in angiogenesis
K Sakai, T Hayashi, Y Sakai, J Mada, K Tonami… - Scientific Reports, 2023 - nature.com
… three-dimensional mathematical model for the dynamics of vascular endothelial cells during
sprouting angiogenesis… model for simulating three-dimensional angiogenic morphogenesis. …
sprouting angiogenesis… model for simulating three-dimensional angiogenic morphogenesis. …
Angiogenic factors produced by hypoxic cells are a leading driver of anastomoses in sprouting angiogenesis–a computational study
M Moreira-Soares, R Coimbra, L Rebelo, J Carvalho… - Scientific reports, 2018 - nature.com
… in this three dimensional model is simulated in a box of size 250 × 250 × 125 μm 3 , it starts
from a central capillary 72 , and the new sprouts grow along the gradient of angiogenic factor…
from a central capillary 72 , and the new sprouts grow along the gradient of angiogenic factor…
[HTML][HTML] 3D hybrid modelling of vascular network formation
… we develop a three-dimensional (3D), off-lattice, hybrid model of … and capillary sprout
formation, our hybrid model allows us to … the model to account for the action of anti-angiogenic …
formation, our hybrid model allows us to … the model to account for the action of anti-angiogenic …
Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis
… that models endothelial cells (EC) as physical agents on a discrete three-dimensional
grid. The coordinates of the agents and events such as proliferation and migration occur in …
grid. The coordinates of the agents and events such as proliferation and migration occur in …
Simulation of angiogenesis in three dimensions: development of the retinal circulation
JP Alberding, TW Secomb - Bulletin of Mathematical Biology, 2023 - Springer
… The model shows how stochastic generation of vascular sprouts combined with a set of …
of a specialized three-dimensional vascular structure with a high degree of organization. …
of a specialized three-dimensional vascular structure with a high degree of organization. …
[HTML][HTML] Modelling tumor-induced angiogenesis: combination of stochastic sprout spacing and sprout progression
F Hosseini, N Naghavi - Journal of Biomedical Physics & …, 2017 - ncbi.nlm.nih.gov
… tumor angiogenic factors (TAFs). We perform simulations of the siting of capillary sprouts on
an … approximation of the dynamic equations of some angiogenesis activators and inhibitors. …
an … approximation of the dynamic equations of some angiogenesis activators and inhibitors. …
Coupled hybrid continuum-discrete model of tumor angiogenesis and growth
J Lyu, J Cao, P Zhang, Y Liu, H Cheng - PloS one, 2016 - journals.plos.org
… vessel accumulate to form capillary sprouts, which move towards … model into a three-dimensional
space. Wu et al.[12] presented a three-dimensional model of solid tumor angiogenesis …
space. Wu et al.[12] presented a three-dimensional model of solid tumor angiogenesis …
Computational modeling of angiogenesis: The importance of cell rearrangements during vascular growth
… ), whereas highly stiff or dense matrices significantly limit sprout elongation in three-dimensional
environments (Shamloo & Heilshorn, 2010). At the same time, EC migration remodels …
environments (Shamloo & Heilshorn, 2010). At the same time, EC migration remodels …
The impact of endothelial cells proliferation in a multiscale realistic reproduction of angiogenesis
H Salavati, M Soltani - Biochemical engineering journal, 2019 - Elsevier
… the sprouting angiogenesis. The model is a hybrid, which a lattice-based cellular Potts model
reproduces … Shirinifard et al. presented a three dimensional cell-based model to study on …
reproduces … Shirinifard et al. presented a three dimensional cell-based model to study on …
Heterotypic multicellular spheroids as experimental and preclinical models of sprouting angiogenesis
IV Vakhrushev, EK Nezhurina, PA Karalkin… - Biology, 2021 - mdpi.com
… on these results, we are currently developing an assay for studying the migration,
proliferation, and differentiation of human endothelial and pericyte-like cells in three-dimensional …
proliferation, and differentiation of human endothelial and pericyte-like cells in three-dimensional …