… We reported the first large-scale and comprehensive genomic data … Somatic mutation
landscape of 65 prostate cancer patients … This analysis revealed that low expression of SLIT2 was …

… from RNA sequencing (RNA-seq) data. The mutational landscape of 3,217 primary breast
cancer … Large-scale projects such as TCGA and SCAN-B generate vast amounts of data, but …

… samples, enabling studies of somatic mutagenesis in large-scale cohorts, across genetic …
inferred from the sequencing data (using Piccard’s software). This analysis revealed that, for …

… whole exome sequencing and transcriptome sequencing, we … GO analysis revealed that the
mutated genes were most relevant to … , creating a large-scale change of tumor transcriptome. …

… large-scale prospective clinical sequencing program using the Fudan-BC panel, and
comprehensively analyze the clinical and genomic … A pairwise analysis revealed that the PI3K and …

… Large-scale studies analyzing DNA sequencing data are needed to better distinguish … the
disease while considering the nonpathogenic landscape of mutations. Such findings may have …

… of the genomic landscape of primary and metastatic PCa, enabled by recent large-scale
sequencing … In a 2015 report, the authors used single-cell RNA sequencing on 76 CTCs from 12 …

… Here we provide a whole-genome landscape of somatic … Our comprehensive analysis
identified point mutations, structural … However, large-scale analysis of noncoding mutations and …

… enrichment of mutations in coding and putative regulatory regions. Our analysis reveals that
the first cell division after fertilization produces ~3.4 mutations, followed by 2–3 mutations in …

… Using whole-transcriptome sequencing, we analyzed RNA from granulocytes of 104 … for
which mutations in the splicing machinery have been described. This analysis revealed that the 3…