Towards a map of cis-regulatory sequences in the human genome
… a good understanding of coding sequences in the human reference genome. In contrast,
although cis-regulatory sequences are as important as coding sequences in specifying various …
although cis-regulatory sequences are as important as coding sequences in specifying various …
A map of cis-regulatory modules and constituent transcription factor binding sites in 80% of the mouse genome
… However, the power of such comparative genomics approach is hampered in … cis-regulatory
sequences due to the lack of a good understanding of mouse orthologous sequences and …
sequences due to the lack of a good understanding of mouse orthologous sequences and …
Transposable elements as a potent source of diverse cis-regulatory sequences in mammalian genomes
V Sundaram, J Wysocka - Philosophical Transactions of …, 2020 - royalsocietypublishing.org
… substrate for evolving diverse cis-regulatory elements for the host, most genomic TEs are …
60% in the human and mouse genomes) is located in introns [95]. For genes that are active, …
60% in the human and mouse genomes) is located in introns [95]. For genes that are active, …
A map of cis-regulatory elements and 3D genome structures in zebrafish
… We converted the cis-regulatory elements from zebrafish genomic locations(danRer10) to
human and mouse genomic locations (hg38 and mm10, respectively), using the liftOver tools …
human and mouse genomic locations (hg38 and mm10, respectively), using the liftOver tools …
[HTML][HTML] The cis-regulatory atlas of the mouse immune system
… ) expression to the genome-wide accessibility … cis-regulatory elements where binding of
given TFs is likely functionally relevant, validated by chromatin immunoprecipitation sequencing (…
given TFs is likely functionally relevant, validated by chromatin immunoprecipitation sequencing (…
A compendium and comparative epigenomics analysis of cis-regulatory elements in the pig genome
… more than 220,000 cis-regulatory elements in the pig genome. Surprisingly, … cis-regulatory
elements between human and pig genomes than those between human and mouse genomes…
elements between human and pig genomes than those between human and mouse genomes…
Hold out the genome: a roadmap to solving the cis-regulatory code
CG de Boer, J Taipale - Nature, 2024 - nature.com
… In this Perspective article, we focus on how cis-regulatory DNA sequences control gene
transcription rates via interactions between transcription factors and chromatin. Although the …
transcription rates via interactions between transcription factors and chromatin. Although the …
Cis-regulatory sequences in plants: their importance, discovery, and future challenges
… , but also distinct, molecular signatures at cis-regulatory sequences compared to animals.
Although in plant species with smaller genomes, such as Arabidopsis thaliana (Arabidopsis), …
Although in plant species with smaller genomes, such as Arabidopsis thaliana (Arabidopsis), …
Characterizing cis-regulatory elements using single-cell epigenomics
… Cell type-specific gene expression patterns and dynamics during development or in
disease are controlled by cis-regulatory elements (CREs), such as promoters and enhancers. …
disease are controlled by cis-regulatory elements (CREs), such as promoters and enhancers. …
Massively parallel cis-regulatory analysis in the mammalian central nervous system
SQ Shen, CA Myers, AEO Hughes, LC Byrne… - Genome …, 2016 - genome.cshlp.org
… retina by ex vivo plasmid electroporation and into the mouse cerebral cortex by in vivo
AAV injection. We demonstrate tissue-specific cis-regulatory activity of DHSs and provide …
AAV injection. We demonstrate tissue-specific cis-regulatory activity of DHSs and provide …