… used in anti-angiogenic therapy combining α5β1 and VEGF inhibition, and has been shown
to be … motif, and this integrin α5β1/ligand binding modulates diverse cellular progression by …

… mechanisms, including integrin expression regulation, … factor (VEGF), through VEGF receptor
2 signaling, activates the … factors and cytokines activate and modulate tumor cell migration …

… to virion–integrin interactions may be modulated by a host of … signaling and downstream
cellular responses due to that … endothelial growth factor (VEGF), at least six integrins, α V β 3 , α …

… VEGF receptor-2 by promoting its activation through integrin α v β 3 , a molecule that is also
required for VEGF-… regulate basic cellular functions, whereas inside-out activation modulates …

… /opsin/VEGF transgenic mice showed severe retinal detachment and higher integrin α5β1
… of Tet/opsin/VEGF transgenic mice treated with doxycycline as well as in HRECs exposed to …

… trafficking also facilitates matrix remodelling and modulates growth factor receptor (GFR) …
) support adhesion to laminin through VEGF-induced and PDZ-protein-dependent activation of …

… the response to conventional cancer therapy (5). Antiangiogenic therapy neutralizing VEGF,
or … Most importantly, we define a new mechanism of modulation of integrin activity during …

… but eventually succumbs to tumor modulation by supporting cancer … AKT signaling and
consequent VEGF synthesis in cancer … C activation, GTPases activation and triggering of integrin …

… VEGFR-2 and integrin β3 appears to be synergistic, because VEGFR-2 activation induces
integrin β3 tyrosine phosphorylation, which, in turn, is crucial for VEGF-induced tyrosine …

… Integrins are the main cellular adhesion receptors that through multifaceted roles as …
Altered integrin expression is frequently detected in tumours, where integrins have roles in …