High-throughput Screening of Toxic Chemicals on Neural Stem Cells

K Farrell, P Joshi, A Roth, C Kothapalli, MY Lee - 2016 - books.rsc.org
… a microfluidic array platform providing in vivo-like 3D niche conditions for the study of NSC
self-renewal and … hypoxic) culture conditions, and its effects on hNSC self-renewal and …

Human blood serum induces p38-MAPK-and Hsp27-dependent migration dynamics of adult human cardiac stem cells: Single-cell analysis via a microfluidic-based …

AL Höving, J Schmitz, KE Schmidt, JFW Greiner… - Biology, 2021 - mdpi.com
Quantitative assessment of the covered tracks showed a significant increase in the migrated
… a p38-dependent migration of mouse neural stem cells [27]. Other groups reported p38-…

Stem Cell-Based Modeling of Early Human Neural Development

X Xue - 2020 - deepblue.lib.umich.edu
… of distinct classes of neuronal progenitor cells located at defined … stem cells (ESCs)
and induced pluripotent stem cells (iPSCs), due to their pluripotency and unlimited self-renewal

Micro/nanoengineered technologies for human pluripotent stem cells maintenance and differentiation

SN Esfahani, AMR Irizarry, X Xue, SBD Lee, Y Shao… - Nano Today, 2021 - Elsevier
… regulates their self-renewal and differentiation will be … Finally, we discuss the application
of microfluidic devices for … and quantitative results are showing PAX6 + neural epithelial …

Micro-engineering of embryonic stem cells niche to regulate neural cell differentiation

R Joshi - 2018 - rave.ohiolink.edu
… This is because ESCs have unlimited self-renewal and … This study provided a model for
quantitative studies of … /or differentiate the resulting neural stem cells into specific cell lineages. …

Multiplexed analysis of neural cytokine signaling by a novel neural cellcell interaction microchip

MAA Abdullah, N Amini, L Yang, JL Paluh, J Wang - Lab on a Chip, 2020 - pubs.rsc.org
arrays in high throughput microfluidic platforms that allows … the NCCIM assay for evaluating
neural progenitor cells. (a) … prior to differentiation and impacts self-renewal, 44 MKI67 (ki67) …

[HTML][HTML] An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates

J Tischler, Z Swank, HA Hsiung, S Vianello… - … reports methods, 2022 - cell.com
… Overlaying a custom microwell array with microfluidic … of organoid cultures for further
analyses. However, the required … profiles, derived from quantitative analyses of fluorescent time-…

Three-Dimensional Human Neural Stem Cell Culture for High-Throughput Assessment of Developmental Neurotoxicity

P Joshi - 2019 - engagedscholarship.csuohio.edu
microfluidic array platform providing in vivo-like 3D niche conditions for the study of NSC …
with lentiviruses and monitored over time for self-renewal and differentiation. The red-colored …

Biochemical analysis on microfluidic chips

J Wu, Z He, Q Chen, JM Lin - TrAC Trends in Analytical Chemistry, 2016 - Elsevier
quantitative analysis on the chip-MS system, we developed a stable isotope labeling assisted
microfluidic … Hematopoietic stem and progenitor cells could be retained in the engineering …

Highly parallelized human embryonic stem cell differentiation to cardiac mesoderm in nanoliter chambers on a microfluidic chip

AR Vollertsen, SA Den, V Schwach… - Biomedical …, 2021 - Springer
… Here, we show that we can differentiate human embryonic stem cells (hESCs) to early … For
example, human neuronal stem cell culture has been shown to result in widespread cell death …