Phase 2a clinical trial of mitochondrial protection (elamipretide) during stent revascularization in patients with atherosclerotic renal artery stenosis
… ischemic renal injury and improves renal outcomes after … -2 (tissue inhibitor of
metalloproteinases-2) at 24 hours after … and inhibits mitochondrial permeability transition pore …
metalloproteinases-2) at 24 hours after … and inhibits mitochondrial permeability transition pore …
Renal revascularization attenuates myocardial mitochondrial damage and improves diastolic function in pigs with metabolic syndrome and renovascular hypertension
RA Farahani, S Yu, CM Ferguson, XY Zhu… - Journal of …, 2022 - Springer
… function by PTRA ameliorated myocardial mitochondrial damage and diastolic dysfunction …
that 4 weeks after technically successful renal revascularization, cardiomyocyte mitochondrial …
that 4 weeks after technically successful renal revascularization, cardiomyocyte mitochondrial …
Mitochondrial protective agents for ischemia/reperfusion injury
RA Kloner - Circulation: Cardiovascular Interventions, 2017 - Am Heart Assoc
… keep the mitochondrial permeability transition pore closed and … single-kidney blood flow,
and improved kidney function in … n=14); both revascularization and contrast injection were done …
and improved kidney function in … n=14); both revascularization and contrast injection were done …
The mitochondrial permeability transition pore: an evolving concept critical for cell life and death
G Morciano, N Naumova, P Koprowski… - Biological …, 2021 - Wiley Online Library
… an unspecific increase in permeability of the … kidney cell injury caused by mPTP opening
is provided by Bendavia, a mPTP inhibitor, which inhibits damage caused by revascularization …
is provided by Bendavia, a mPTP inhibitor, which inhibits damage caused by revascularization …
[HTML][HTML] Physiopathology of the permeability transition pore: Molecular mechanisms in human pathology
… opening of the mitochondrial permeability transition pore complex (… revascularization had
no effect on ST-segment resolution or cardiac enzymes and did not improve clinical outcome. …
no effect on ST-segment resolution or cardiac enzymes and did not improve clinical outcome. …
Improved renal outcomes after revascularization of the stenotic renal artery in pigs by prior treatment with low-energy extracorporeal shockwave therapy
XJ Chen, X Zhang, K Jiang, JD Krier, X Zhu… - Journal of …, 2019 - journals.lww.com
… the stenotic kidney, but its ability to improve renal function and structure after revascularization
… We tested the hypothesis that a LE-SWT regimen before percutaneous transluminal renal …
… We tested the hypothesis that a LE-SWT regimen before percutaneous transluminal renal …
[HTML][HTML] Tubular mitochondrial dysfunction, oxidative stress, and progression of chronic kidney disease
M Fontecha-Barriuso, AM Lopez-Diaz… - Antioxidants, 2022 - mdpi.com
… production and mitochondrial permeability transition pore (… mitochondrial biogenesis and
improved kidney function after … artery stent revascularization, it increased peripheral venous …
improved kidney function after … artery stent revascularization, it increased peripheral venous …
Renovascular disease induces mitochondrial damage in swine scattered tubular cells
AA Nargesi, XY Zhu, SM Conley… - … Physiology-Renal …, 2019 - journals.physiology.org
… of the mitochondria permeability transition pore, and exerts protective effects on the kidney
… We found that Lean STCs improved survival of injured PK1 cells, underscoring the potential …
… We found that Lean STCs improved survival of injured PK1 cells, underscoring the potential …
Kidney intrinsic mechanisms as novel targets in renovascular hypertension
… A mitochondrial permeability transition pore inhibitor improves renal outcomes after
revascularization in … growth factor improves renal outcomes following revascularization. Am J …
revascularization in … growth factor improves renal outcomes following revascularization. Am J …
Mitochondrial dysfunction and the AKI-to-CKD transition
M Jiang, M Bai, J Lei, Y Xie, S Xu… - … of Physiology-Renal …, 2020 - journals.physiology.org
… opening of mitochondrial permeability transition pores, loss of … or inhibit mitochondrial
permeability transition. By inhibiting … 4 wk after ischemia significantly improves renal fibrosis after …
permeability transition. By inhibiting … 4 wk after ischemia significantly improves renal fibrosis after …