Non-alcoholic fatty liver disease, insulin resistance, metabolic syndrome and their association with vascular risk

E Muzurović, DP Mikhailidis, C Mantzoros - Metabolism, 2021 - Elsevier
… by NAFLD. Insulin resistance (IR) and fat accumulation in the liver are strongly related…
The association between NAFLD, metabolic syndrome (MetS) and IR is established, but an …

Mechanisms of non-alcoholic fatty liver disease in the metabolic syndrome. A narrative review

L Rinaldi, PC Pafundi, R Galiero, A Caturano… - Antioxidants, 2021 - mdpi.com
… Both MS and NAFLD are metabolic disorders with a high clinical … Insulin resistance state
occurring when cells in muscles, fat … In addition, in animal models, if methyl-donor micronutrients …

Redox regulation of metabolic syndrome: recent developments in skeletal muscle insulin resistance and non-alcoholic fatty liver disease (NAFLD)

YH Yeo, YC Lai - Current opinion in physiology, 2019 - Elsevier
… muscle in a mouse model of diet-induced insulin resistance [1… attenuate skeletal muscle
insulin resistance in mice with heart … skeletal muscle insulin resistance in mice fed a high-fat diet (…

Non-alcoholic fatty liver disease: cause or effect of metabolic syndrome

C Grander, F Grabherr, AR Moschen, H Tilg - Viszeralmedizin, 2016 - karger.com
insulin resistance, innate immunity, metabolic inflammation, and the microbiota are of relevance.
NAFLD, metabolic syndrome (… effects in various animal models of liver inflammation. We …

[PDF][PDF] Ceramides: a cause of insulin resistance in nonalcoholic fatty liver disease in both murine models and humans

H Yki‐Järvinen - Hepatology, 2020 - Wiley Online Library
… In numerous murine models, the liver accumulates TGs without becoming … Hepatic ceramides
dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease. …

An animal model for the juvenile non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

V Marin, N Rosso, M Dal Ben, A Raseni, M Boschelle… - PloS one, 2016 - journals.plos.org
metabolic syndrome and obesity even at young age (< 5 years-old) is threatening the public
health system. The metabolic syndrome, … , female mice never developed insulin resistance

Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease

AJ Engstler, T Aumiller, C Degen, M Dürr, E Weiss… - Gut, 2016 - gut.bmj.com
… To further investigate mechanisms involved in the increased fasting plasma ethanol levels
found in children with early signs of NAFLD, a mouse model of genetically obese ob/ob mice

mTOR activation in liver tumors is associated with metabolic syndrome and non-alcoholic steatohepatitis in both mouse models and humans

T Okuno, A Kakehashi, N Ishii, M Fujioka, M Gi… - Cancers, 2018 - mdpi.com
mouse models to human HCCs, we performed the immunohistochemical evaluation of mTOR
in metabolic syndrome/… have been reported to improve insulin resistance and NASH in rats …

Crosstalk between adipose tissue insulin resistance and liver macrophages in non-alcoholic fatty liver disease

C Rosso, K Kazankov, R Younes, S Esmaili… - Journal of …, 2019 - Elsevier
… More recently, data derived from animal models and in vitro … hepatic insulin sensitivity
by inhibiting insulin signaling and … the most common feature of the metabolic syndrome (MetS), …

The interplay between insulin resistance, inflammation, oxidative stress, base excision repair and metabolic syndrome in nonalcoholic fatty liver disease

S Ziolkowska, A Binienda, M Jabłkowski… - International Journal of …, 2021 - mdpi.com
… of NAFLD in animal models and … : NAFLD, fatty liver, nonalcoholic fatty liver, nonalcoholic
steatohepatitis, Kupffer cells, insulin resistance, metabolic syndrome, T2DM, obesity, liver