… CHS3 is a TNL with additional integrated domains (LIM (Lin-… Mec-3 domain) domain and
putative DA-1 protease domain) at … CHS3 are necessary for triggering autoimmune cell death in …

… cell death, but the direct mechanisms leading to such deregulation remains unclear. Here,
we found that the TIR-NBS-LRR protein … cell death in bak1-4 and bak1-4 bir3-2 mutants via …

… A mutant CHS3 protein with TIR‐NB‐LRR‐LIM domains modulates growth, cell death and
freezing tolerance in a temperature‐dependent manner in Arabidopsis. The Plant Journal, 63(…

… N- and C-termini (TIR/CC and LRR) differ in the context of each … Additionally to that,
bir2-mutants reveal elevated cell death … the cell death occurring in bir2-mutants, double-mutants …

… (ID) with homology to regulatory domains, which is … two cell-death regulatory modes for
CHS3/CSA1 pairs. One is mediated by ID domain on clade 1 CHS3, and the other relies on CHS3…

… activity is important for TIRmediated cell death. Nicotinamide, … For example, TNL protein
CHS3 contains a LIM domain at its … mutation in csa1 can suppress bak1 bir3mediated cell death. …

… with dwarfism and often spontaneous cell death. In this review, … CHS3 contains a LIM domain
at its C-terminus. A missense … that mutations in slh1 and chs3-2D are sensed by the TIR-NB-…

… domain swaps with several DA1 homologs, we show that the LIM-peptidase domain of the
family member CHS3/… mechanisms by which effectors modulate plant processes is enabling …

… (TIR) domain NLR receptors to confer host cell death and … proteins to modulate membrane
ion fluxes and execute host … -L1 adr1-L2 triple mutant in Arabidopsis basal and TIR-NLR-…

… include mutants of the Toll/interleukin-1 receptor (TIR)-NLRs, … mutants we tested induced
visible macroscopic cell death (… , T-DNA insertion or deletion mutants including chs3-2, where …