[HTML][HTML] Discovery of New Compounds Active against Plasmodium falciparum by High Throughput Screening of Microbial Natural Products

G Pérez-Moreno, J Cantizani, P Sánchez-Carrasco… - PloS one, 2016 - journals.plos.org
… In summary, the compounds identified in the present natural products screening provide
valuable information for antimalarial drug discovery from microbial sources. Although the most …

[HTML][HTML] High-throughput screening of natural product and synthetic molecule libraries for antibacterial drug discovery

NJ Ayon - Metabolites, 2023 - mdpi.com
… lack of new and promising antibiotics, bacterial infection has … High-throughput screening
(HTS) allows rapid screening of a … different approaches to HTS for antibacterial drug screening

High-throughput screening platform for the discovery of new immunomodulator molecules from natural product extract libraries

J Perez del Palacio, C Díaz… - … Screening, 2016 - journals.sagepub.com
… on an high-throughput screening of microbial natural product extracts for the discovery of …
with immunomodulatory properties meeting the demanding requirements of HTS drug discovery

New approaches to antimicrobial discovery

K Lewis - Biochemical pharmacology, 2017 - Elsevier
drug discovery presents an unusually difficult intellectual challenge, simply doing more
high-throughput screening … (C) iChip for high throughput microbial cultivation in situ. The iChip is …

[HTML][HTML] Natural products in drug discovery: advances and opportunities

AG Atanasov, SB Zotchev, VM Dirsch… - … reviews Drug discovery, 2021 - nature.com
natural product (NP)-based drug discovery shown in green boxes. The process begins with
extraction of NPs from organisms such as bacteriahigh-throughput screening, crude extracts

[HTML][HTML] Current screening methodologies in drug discovery for selected human diseases

OM Lage, MC Ramos, R Calisto, E Almeida… - Marine drugs, 2018 - mdpi.com
… -resistant bacteria implies re-inventing the wheel on drug discovery. A … to be a new approach
of antimicrobial chemotherapy. … High-throughput screening for anticancer compounds are …

[HTML][HTML] Natural products for drug discovery in the 21st century: innovations for novel drug discovery

NE Thomford, DA Senthebane, A Rowe… - International journal of …, 2018 - mdpi.com
… of many microorganisms for potential antibiotics [29]. Indeed, … Using this new approach,
it is possible to identify several … the utilisation of data from high throughput screening [170,171]. …

[HTML][HTML] Innovative omics-based approaches for prioritisation and targeted isolation of natural products–new strategies for drug discovery

JL Wolfender, M Litaudon, D Touboul… - Natural product …, 2019 - pubs.rsc.org
… to working with crude natural extracts because of their complex … of high-throughput screening
campaigns. In line with the … approaches, NMR has been used for microorganism extract

[HTML][HTML] High-throughput screening of biodiversity for antibiotic discovery

SS Terekhov, IA Osterman… - Acta Naturae …, 2018 - cyberleninka.ru
… modern technologies of drug discovery. Combinatorial chemistry approaches are based on
… for screening for antibiotic-resistant bacteria [62] or bacteriolytic activity [63]. This alternative …

Natural products in drug discovery

AA Koparde, RC Doijad… - Pharmacognosy-medicinal …, 2019 - books.google.com
… importance of natural products from plants and microorganisms in … In four different ways,
medicinal plants having good … principle of high-throughput screening of large amount of natural