… In a continued effort to develop potent cholesterol esterase (… Inspired by various biological
attributes of flavones, we have … of the literature value for a phosphorylated flavonoid (PF, IC 50 …

… bitter melon and its juice have potent cholesterol-lowering and liver triacylglycerol activities
… , saponins and flavonoids in BMAE. A series of phosphorylated flavones as potential …

… serine hydrolase that primarily originated from pancreas and lactating glands of higher …
cholesterol esterase inhibitors for the first time. The best ligand identified exhibited not only potent …

… , indicating strong antitumor efficacy. The inhibitory effect of … phosphorylated flavonoids can
mimic the transition state of … be employed as pancreatic cholesterol esterase inhibitors [20]…

… synthesized ester phosphorylated flavonoids as inhibitors of pancreatic cholesterol esterase
… The study revealed that the modified flavonoids showed remarkable potency against those …

… the synthesized flavonoids (QDP), we have successfully demonstrated the photochemical
synthesis of … The overall goal of the project is to synthesize new flavonoid (mainly flavones and …

… potent inhibitory activity against pancreatic cholesterol … for retarding pancreatic cholesterol
esterase have not been … their relative effectiveness against pancreatic cholesterol esterase by …

… We have synthesized nineteen phosphorylated flavonoids … and selective inhibitor of pancreatic
cholesterol esterase (CEase) … potency, 11 much better than the parent flavonoids. These …

… cholesterol esterase, binding bile acids, and decreasing the … In terms of lipid metabolic
disorders, flavonoids have been … expression, decreased AMPK phosphorylation, and decreased …

… Unpon decarboxylation of 3– phospho–5– pyrophospho mevalonate by pyro phospho …
back to free cholesterol by the action of cholesterol esterase, a pancreatic cholesteryl ester …