A robust data-driven genomic signature for idiopathic pulmonary fibrosis with applications for translational model selection
R Ammar, P Sivakumar, G Jarai, JR Thompson - PLoS One, 2019 - journals.plos.org
… to the disease signature. Our work defines a robust genetic signature for IPF providing a …
as enables the identification of preclinical models that most closely resemble human IPF. …
as enables the identification of preclinical models that most closely resemble human IPF. …
Molecular signatures of idiopathic pulmonary fibrosis
IR Konigsberg, R Borie, AD Walts… - American journal of …, 2021 - atsjournals.org
… Volcano plots depicting features that are statistically significant in idiopathic pulmonary
fibrosis (IPF) lung tissue compared with control lung tissue at a false discovery rate <0.05 (blue …
fibrosis (IPF) lung tissue compared with control lung tissue at a false discovery rate <0.05 (blue …
[HTML][HTML] A novel prognostic signature for idiopathic pulmonary fibrosis based on five-immune-related genes
L Qiu, G Gong, W Wu, N Li, Z Li, S Chen… - … of Translational …, 2021 - ncbi.nlm.nih.gov
… Therefore, we constructed a molecular genomic signature to predict the prognosis of IPF …
the performance of the genomic signature in the validation cohort. The signature showed an …
the performance of the genomic signature in the validation cohort. The signature showed an …
MicroRNA and protein-coding gene expression analysis in idiopathic pulmonary fibrosis yields novel biomarker signatures associated to survival
NG Casanova, T Zhou, ML Gonzalez-Garay… - Translational …, 2021 - Elsevier
… (miRNA) gene signatures as biomarkers in patients with Idiopathic pulmonary fibrosis (IPF), …
identify potential miRNA or gene signatures to serve as novel biomarkers for survival in IPF …
identify potential miRNA or gene signatures to serve as novel biomarkers for survival in IPF …
Detecting the molecular system signatures of idiopathic pulmonary fibrosis through integrated genomic analysis
I Gangwar, N Kumar Sharma, G Panzade, S Awasthi… - Scientific reports, 2017 - nature.com
… Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing IIP that has no effective therapy with
a mortality rate higher than many cancers; median survival from the time of diagnosis being …
a mortality rate higher than many cancers; median survival from the time of diagnosis being …
The peripheral blood proteome signature of idiopathic pulmonary fibrosis is distinct from normal and is associated with novel immunological processes
… Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal … Thus, in this paper we apply
a novel large scale high … to identify a unique IPF proteome signature and give insight into …
a novel large scale high … to identify a unique IPF proteome signature and give insight into …
Genome-wide association study across five cohorts identifies five novel loci associated with idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic lung condition with poor survival times. We
previously published a genome-… size estimates, we performed a genome-wide meta-analysis …
previously published a genome-… size estimates, we performed a genome-wide meta-analysis …
Pan-transcriptome-based candidate therapeutic discovery for idiopathic pulmonary fibrosis
… nintedanib, for treatment of patients with idiopathic pulmonary fibrosis (IPF). However, neither
… minimal effect on IPF-specific gene signature or alter translational modifications involved in …
… minimal effect on IPF-specific gene signature or alter translational modifications involved in …
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
… Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease characterized by epithelial
injury and chronic activation of invasive fibroblasts that deposit and remodel the extracellular …
injury and chronic activation of invasive fibroblasts that deposit and remodel the extracellular …
Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis
P Sivakumar, R Ammar, JR Thompson, Y Luo… - Respiratory …, 2021 - Springer
… translational biomarker studies. Transcriptomic and proteomic disease signatures generated
from clinically relevant human … ” modeling can enable translational disease understanding, …
from clinically relevant human … ” modeling can enable translational disease understanding, …