Connexins and their channels in inflammation

J Willebrords, S Crespo Yanguas, M Maes… - Critical reviews in …, 2016 - Taylor & Francis
… LPS activates c-jun terminal kinases 1 and 2, p38 and extracellular signal-regulated kinases
1 and 2, yet it also abrogates GJ coupling in endothelial cells isolated from wild-type, Cx37 −…

Genome-wide DNA methylation profiles may reveal new possible epigenetic pathogenesis of sporadic congenital cataract

S Liu, C Hu, Y Luo, K Yao - Epigenomics, 2020 - Future Medicine
extracellular spaces and intracellular vacuoles. A possible reason for this is that loss of the
gap junction-mediated intercellular communication disturbs the osmotic balance in the lens. …

[HTML][HTML] Functional non-coding polymorphism in an EPHA2 promoter PAX2 binding site modifies expression and alters the MAPK and AKT pathways

X Ma, Z Ma, X Jiao, JF Hejtmancik - Scientific reports, 2017 - nature.com
… These results clearly show that EPHA2 plays critical roles in lens transparency, although …
role in lens development and cataractogenesis 24, 25 , the functional role of PAX2 in the lens

[HTML][HTML] ErbBs in Lens Cell Fibrosis and Secondary Cataract

JK VanSlyke, BA Boswell… - … ophthalmology & visual …, 2023 - iovs.arvojournals.org
… markers of lens fiber cells. Although several types of physiologically relevant growth factors
can stimulate lens fiber cell differentiation in primary lens epithelial cells (eg, FGF, BMP, IGF1)…

Na+/K+-ATPase Drives Most Asymmetric Transports and Modulates the Phenotype of Epithelial Cells

I Larre, M Cereijido, O Paez, L Shoshani… - Studies of Epithelial …, 2020 - Springer
… of MDCK with 10 nM ouabain increases the intercellular communication through Gap
Junctions (ICGJ). This response occurs within minutes and reaches a peak after 1 h (Fig. 1.5d, e). …

[HTML][HTML] In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment

A Lamouline, S Bersini, M Moretti - Frontiers in Oncology, 2023 - frontiersin.org
… a tyrosine kinase inhibitor (ie Nindetanib, targeting VEGF, FGF … to create gap junctional
intercellular communications (GJICs) … protein/extracellular-signal-regulated kinases (MAPK/ERK) …

The Intersecting Function of Connexin43 and Runx2 in Bone

AML Buo - 2017 - search.proquest.com
… bone cell function via the gap junction-mediated sharing of second … of extracellular
signal-regulated kinase (ERK) and protein … testing, but they highlight a novel role of Cx43 as an …

Putative Pore-lining Residues and Intracellular Magnesium Influence Connexin50 Unitary Gap Junction Channel Conductance

S Sudhakar - 2016 - search.proquest.com
… Stem cells in the lens equator also replenish lens fiber cells to … A novel role for FGF and
extracellular signal-regulated kinase in gap junction-mediated intercellular communication in the …

Na+/K+-ATPase Drives Most Asymmetric Transports and Modulates the Phenotype of Epithelial Cells

M Cereijido, I Larre, O Paez, L Shoshani… - Ion Channels and …, 2016 - Springer
… nM ouabain increases cell-cell communication by up to 510 % in 1 h (unpublished results).
Therefore, ouabain should be listed among hormones that influence cell-cell communication, …

[PDF][PDF] Ionizing radiation induced cataracts: Recent biological and mechanistic developments and perspectives for future research

EAASB Scott, BCDMJ Sarah, KRT Joseph… - 2016 - academia.edu
… in the lens cortex and, as the lens ages, its permeability to oxygen … the communication
between irradiated cells and unirradiated cells could be through direct intercellular communication