The m7G Reader NCBP2 Promotes Pancreatic Cancer Progression by Upregulating MAPK/ERK Signaling
J Xie, T Mo, R Li, H Zhang, G Liang, T Ma, J Chen… - Cancers, 2023 - mdpi.com
… , NCBP2 and NCBP1 form the cap-binding complex (CBC), … Like NCBP2, NCBP3 can substitute
NCBP2 to bind with … -end processing, pre-mRNA splicing, nuclear-cytoplasmic transport, …
NCBP2 to bind with … -end processing, pre-mRNA splicing, nuclear-cytoplasmic transport, …
Condensation of a nuclear mRNA export factor regulates mRNA transport during stress
S Heinrich, M Hondele, D Marchand, CP Derrer… - Biorxiv, 2022 - biorxiv.org
… cap-binding complex (CBC), comprising Cbc1 (CBP80 in vertebrates) and Cbc2 (CBP20),
which binds co-transcriptionally … poly(A) tail of the pre-mRNA and is involved in nuclear mRNA …
which binds co-transcriptionally … poly(A) tail of the pre-mRNA and is involved in nuclear mRNA …
mRNA-based therapeutics in cancer treatment
H Sun, Y Zhang, G Wang, W Yang, Y Xu - Pharmaceutics, 2023 - mdpi.com
… It can bind to the 40S subunit of the ribosome and initiate translation of CDS, bypassing …
Polyadenylation of pre-mRNA in eukaryotic cells occurs after transcription and before transport …
Polyadenylation of pre-mRNA in eukaryotic cells occurs after transcription and before transport …
Making Ends Meet: Role of the LARP1 La-Module in TOP mRNA Recognition
HA Al-Ashtal - 2020 - search.proquest.com
… The cap is co-transcriptionally incorporated in three steps … In the nucleus, the cap is bound
by nuclear cap-binding complex … required for pre-mRNA processing and accompanies mature …
by nuclear cap-binding complex … required for pre-mRNA processing and accompanies mature …
Discovery and characterization of autoinhibition in the S. pombe decapping complex
DR Paquette - 2017 - escholarship.org
… musicals, keeping me sane and accompanying me on this crazy … upregulation of the YRA1
pre-mRNA and the mRNA encoding … While we were able to quantify cap binding to Y220G, we …
pre-mRNA and the mRNA encoding … While we were able to quantify cap binding to Y220G, we …
[图书][B] Regulation of mRNA decapping across atomic and mesoscopic scales
RW Tibble - 2021 - search.proquest.com
… 5’-3’ decay of pre-mRNA and mRNA targets in budding … 2.3b) and we were able to observe
cap binding in Dcp2core … moreover, we show here that IM2 binds Dcp1:Dcp2core in trans and …
cap binding in Dcp2core … moreover, we show here that IM2 binds Dcp1:Dcp2core in trans and …
Deciphering messenger ribonucleoprotein composition using single molecule resolution microscopy
M Kramar - 2019 - escholarship.mcgill.ca
… CBC is only capable of cap binding as a dimeric complex, as both Cbp20 and Cbp80
individually … Elements encoded within the pre-mRNA act to localize and direct the recruitment of …
individually … Elements encoded within the pre-mRNA act to localize and direct the recruitment of …
[图书][B] Regulation of MycTranscription in 3D: Implications for Tumor Development
I Tzelepis - 2022 - search.proquest.com
… Pre-mRNA molecules are submitted to several … pre-mRNA is still associated with its template,
capping enzymes recognize its 5’ end and the nuclear cap-binding complex proteins bind …
capping enzymes recognize its 5’ end and the nuclear cap-binding complex proteins bind …
HibeRNAtion: HIV-1 RNA metabolism and viral latency
… Nascent viral RNA is processed co-transcriptionally upon 5’ … , a component of the pre-mRNA
spliceosome complex, and were … by LRAs can be accompanied by approaches that target …
spliceosome complex, and were … by LRAs can be accompanied by approaches that target …
[图书][B] Examining the Effects of Translation on the Exon Junction Complex
LA Woodward - 2019 - search.proquest.com
… represent a more nuclear variation of the EJC and bind to SR… complex (EJC), which is
imprinted on RNA during pre-mRNA … and TREX complex, which are co-transcriptionally recruited …
imprinted on RNA during pre-mRNA … and TREX complex, which are co-transcriptionally recruited …