Introduction to Metronomic Chemotherapy

MA Mir, N Jan, S Sofi - … Chemotherapy for Breast Cancer …, 2024 - taylorfrancis.com
… malignancies; and oral VNR for nonsmall cell lung cancer (NSCLC). With … High-dose
celecoxib and metronomic “Low-dose” … chemotherapy combined with bevacizumab and erlotinib in …

[HTML][HTML] Targeting cancer-related inflammation with non-steroidal anti-inflammatory drugs: Perspectives in pharmacogenomics

H Lai, Y Liu, J Wu, J Cai, H Jie, Y Xu… - Frontiers in …, 2022 - frontiersin.org
… In advanced non-small cell lung cancer (NSCLC) patients … clinical trial of stage III colon
cancer, additional celecoxib to … Combined use of celecoxib and erlotinib (EGFR inhibitor) also …

The clinical application of fruquintinib on colorectal cancer

Z Chen, L Jiang - Expert Review of Clinical Pharmacology, 2019 - Taylor & Francis
… on non-small cell lung cancer (NSCLC) and gastric cancer is … First is Cyclooxygenase-2(COX-2)
inhibitor Celecoxib. COX-… to assess the efficacy of fruquintinib in combination with other …

Pharmacological targeting of epithelial-to-mesenchymal transition in colorectal cancer

N Zafari, M Velayati, M Nassiri… - Current …, 2022 - ingentaconnect.com
advanced non-small-cell lung cancer. The results of this … Erlotinib combined with gemcitabine
is the first-line treatment … In a phase II study, 800 mg/day of celecoxib combined with …

A curve-free Bayesian decision-theoretic design for phase Ia/Ib trials considering both safety and efficacy outcomes

S Fan, BL Lee, Y Lu - Statistics in biosciences, 2020 - Springer
… of the trial is to recommend the BOD of several doses of celecoxib combined with
erlotinib at a fixed dose in patients diagnosed with advanced non-small-cell lung cancer (NSCLC). …

Molecular targeted agents for enhancing tumour response

M Baumann, M Krause, V Grégoire - Basic clinical radiobiology, 2018 - taylorfrancis.com
… For Erlotinib, several phase I and phase II studies have … A phase II study of celecoxib in
combination with paclitaxel, … with inoperable stage IIIA/B nonsmall cell lung cancer. Clin …

[HTML][HTML] Statin as a potential chemotherapeutic agent: current updates as a monotherapy, combination therapy, and treatment for anti-cancer drug resistance

N Tilija Pun, CH Jeong - Pharmaceuticals, 2021 - mdpi.com
… with a well-established safety profile and optimal dosing. Statins are inhibitors of HMG-CoA …
in non-small cell lung carcinoma treated with inhibitors; gefitinib and erlotinib because of …

[HTML][HTML] Major hurdles to the use of tyrosine kinase inhibitors in clinical prevention/interception studies: Do preclinical studies with EGFR inhibitors suggest …

KH Dragnev, CPC Dragnev, RA Lubet - … and Developmental Biology, 2023 - frontiersin.org
… intermittent dosing, weekly dosing, or a combination of agents. If … The combination of erlotinib
and celecoxib led to 63% … This makes it more difficult to determine whether the combination

[HTML][HTML] Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer

P Nowak-Sliwinska, L Scapozza, AR i Altaba - … (BBA)-Reviews on Cancer, 2019 - Elsevier
… toxic at lower doses and efficient alone or in combination for a … consistency) of biological
systems, together with the varying … the therapeutic window is essential to ascertain the benefits …

Survivin as a biological biomarker for diagnosis and therapy

Y Li, W Lu, J Yang, M Edwards… - … opinion on biological …, 2021 - Taylor & Francis
cancer (HRPC) cell lines [Citation82] and non-small-cell … of YM155 in combination with the
tyrosine kinase inhibitor erlotinib in … with IL-2, cyclophosphamide and the NSAID celecoxib to …