… efficacy trials and effectiveness trials unlinked, we previously, as part of a group with interest
in clinical trial … integrates both efficacy and effectiveness trials, which we referred to as an “…

… The efficacy of using the primer was also confirmed in a clinical trial carried out with …
consolidated as the most effective tool to promote self-efficacy in preventing childhood diarrhoea …

… We are of course also limited in having only one effectiveness trial to compare with the larger
number of published efficacy trials and subsequent effectiveness trials could differ from the …

… In this particular case, we are confusing the “efficacy” of the treatment in a waitlist-controlled
trial with its “effectiveness” as a routine-care treatment [69]. Many of such misinterpretations …

… , rather than relying on individuals studies, we can improve … al evaluating the comparative
effectiveness of treatments for … comparative efficacy of two active treatments, even if no studies …

… Trial Registry since 2010. We discuss challenges with current trial planning and designs that
are often used in clinical trial … an overview of the global health trials landscape. Finally, we …

… The vast majority of investigations of treatment efficacy and effectiveness over the past 30
to 40 years have used the randomized controlled trial (RCT) design. While factorial designs …

… cohort studies, case–control studies, and pragmatic clinical trials. … on several RWE studies
showing their efficacy and safety, … ) for safety and effectiveness reporting in RWE studies. This …

… III clinical trials, their use in early-phase clinical trials has become … trials that assess the
efficacy of new cancer treatments. … TTF can be an effective endpoint when used alongside OS to …

… We compared analytical efficiency and sensitivity of primer–probe sets by testing tenfold
dilutions (10 6 –10 0 viral RNA copies μl –1 ) of SARS-CoV-2 RNA as well as the SARS-CoV-2 …