Efficacy and safety of once-daily inhaled umeclidinium in Asian patients with COPD: results from a randomized, placebo-controlled study

N Zhong, J Zheng, SH Lee, DA Lipson… - … Obstructive Pulmonary …, 2020 - Taylor & Francis
… This 24-week, Phase III, randomized, double-blind, parallel-group study (GSK study
study, benefits in Asian patients with COPD have also been reported in studies of other LAMAs

Dual therapy strategies for COPD: the scientific rationale for LAMA+ LABA

JS Cohen, MC Miles, JF Donohue… - … obstructive pulmonary …, 2016 - Taylor & Francis
… A dose ranging study of UMEC identified that once-daily dosing at 62.5 or 125 μg was …
being tested with LAMAs such as GLY and novel LAMAs. Previous studies of LAMA/LABAs using …

Efficacy and safety of umeclidinium added to fluticasone propionate/salmeterol in patients with COPD: results of two randomized, double-blind studies

TM Siler, E Kerwin, K Singletary, J Brooks… - … Obstructive Pulmonary …, 2016 - Taylor & Francis
… The LAMA umeclidinium (UMEC, GSK573719; GSK, London, UK) has recently been …
for COPD in the US and EU (Citation7,Citation8). Early dose-ranging studies demonstrated …

[HTML][HTML] Genetic effects on treatment response of umeclidinium/vilanterol in chronic obstructive pulmonary disease

L Condreay, L Huang, E Harris, J Brooks, JH Riley… - Respiratory …, 2016 - Elsevier
… muscarinic antagonists (LAMAs) for chronic obstructive pulmonary disease (COPD) is standard,
but … to umeclidinium (UMEC, a LAMA), vilanterol (VI, a LABA), and combination therapy. …

Inhaled umeclidinium in COPD patients: a review and meta-analysis

RA Pleasants, T Wang, J Gao, H Tang, JF Donohue - Drugs, 2016 - Springer
patients. Umeclidinium provides a safe and effective option as an inhaled LAMA for the
management of COPD… To determine the optimal dose of the agent, dose-ranging studies in …

[HTML][HTML] … of Umeclidinium + Inhaled Corticosteroids/Long-Acting Beta2 Agonists for Patients with COPD: Pooled Results of Randomized Placebo-Controlled Trials

TM Siler, E Kerwin, L Tombs, WA Fahy, I Naya - Pulmonary Therapy, 2016 - Springer
… number of randomized, double-blind clinical trials, … , GSK573719; GSK, London, UK) is a
once-daily LAMA indicated for the maintenance treatment of patients with symptomatic COPD [8…

A randomized, blinded study to evaluate the efficacy and safety of umeclidinium 62.5 μg compared with tiotropium 18 μg in patients with COPD

G Feldman, F Maltais, S Khindri… - … of Chronic Obstructive …, 2016 - Taylor & Francis
… antagonists (LAMAs) are an integral part of management in stable COPD and have been …
) was the only LAMA available for patients with COPD. Citation6 Three other LAMAs, aclidinium …

Evidence-based review of data on the combination inhaler umeclidinium/vilanterol in patients with COPD

TE Albertson, WS Bowman, RW Harper… - … of Chronic Obstructive …, 2019 - Taylor & Francis
… triple (LAMA, LABA, ICS) therapy were randomized to remove the ICS. Citation9 This 26-week,
randomized, double-blind, triple-dummy study was of 1,053 COPD patients who were …

Umeclidinium in chronic obstructive pulmonary disease: latest evidence and place in therapy

KS Babu, JB Morjaria - Therapeutic Advances in Chronic …, 2017 - journals.sagepub.com
… new LAMA currently approved for use in patients with COPDCOPD patients from two phase
III, randomized, double-blind, … Vil trifenatate is a novel selective LABA with bronchodilatory …

A randomised, open-label study of umeclidinium versus glycopyrronium in patients with COPD

T Rheault, S Khindri, M Vahdati-Bolouri… - … Open Research, 2016 - Eur Respiratory Soc
study, although both LAMAs are reported to improve lung function compared with placebo in
patients with moderate-to-very-severe COPD … both LAMAs (UMEC [16, 17], GLYCO [18, 20]). …