Effect of treatment with sacubitril/valsartan in patients with advanced heart failure and reduced ejection fraction: a randomized clinical trial

DL Mann, MM Givertz, JM Vader, RC Starling… - JAMA …, 2022 - jamanetwork.com
… was valsartan, whereas enalapril was the active treatment comparator in the PARADIGM-HF
trial. Although angiotensin-converting enzyme inhibitors and angiotensin receptor blockers

Efficacy and safety of sacubitril‐valsartan in heart failure: a meta‐analysis of randomized controlled trials

H Zhang, T Huang, W Shen, X Xu, P Yang… - … Heart Failure, 2020 - Wiley Online Library
… Sacubitril-valsartan has been shown to … angiotensin receptor blockers in patients with heart
failure (HF) and hypertension. The efficacy and safety of sacubitril-valsartan in patients with

Effects of sacubitril/valsartan in patients with heart failure and chronic kidney disease: a meta-analysis

H Kang, J Zhang, X Zhang, G Qin, K Wang… - European journal of …, 2020 - Elsevier
… in-class angiotensin receptor neprilysin inhibitor (ARNI… study, we systematically analyzed
the available studies investigating the effects of sacubitril/valsartan in patients with heart failure

Effect of angiotensin receptor-neprilysin inhibitor versus valsartan on cardiac status in patients with chronic heart failure with reduced ejection fraction: a randomized …

S Ghafur, MA Zahid, H Sarkar… - Open Journal of …, 2020 - geographical.go2journals.com
… enzyme inhibitor (ACEI), an angiotensin receptor blocker (… of angiotensin receptor neprilysin
inhibitor (ARNi) on cardiac status compared to valsartan in patients with chronic heart failure

Sacubitril–valsartan as a treatment for apparent resistant hypertension in patients with heart failure and preserved ejection fraction

AM Jackson, PS Jhund, IS Anand… - European heart …, 2021 - academic.oup.com
… enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB), … trial using the combined
angiotensin receptor–neprilysin … 160 mg twice daily in a phase 2 randomized trial of 266 patients…

The impact of a dose of the angiotensin receptor blocker valsartan on post‐myocardial infarction ventricular remodelling

K Park, YD Kim, KS Kim, SH Lee, TH Park… - … Heart Failure, 2018 - Wiley Online Library
… In the present study, treatment with the maximal tolerated dose of valsartan did not exhibit
a superior effect on post-MI LV remodelling compared with low-dose treatment and was …

… dose angiotensin receptor blocker or angiotensin-converting enzyme inhibitor in heart failure with reduced ejection fraction: a meta-analysis of randomized trials

JP Rindone, CK Mellen - European Journal of Clinical Pharmacology, 2024 - Springer
… or hospitalization for heart failure in the patients with both … -analyses of randomized trials
in patients with HFrEF that compared … of cardiovascular mortality and worsening heart failure. …

The sacubitril/valsartan, a first-in-class, angiotensin receptor neprilysin inhibitor (ARNI): potential uses in hypertension, heart failure, and beyond

K Kario - Current cardiology reports, 2018 - Springer
… (LCZ696) is superior to angiotensin receptor blocker (ARB) monotherapy for reducing …
PARAMETER study is a multicenter, double-blind, randomized trial with sacubitril/valsartan (…

Beneficial and harmful effects of sacubitril/valsartan in patients with heart failure: a systematic review of randomised clinical trials with meta-analysis and trial …

EE Nielsen, JB Feinberg, FL Bu, MH Olsen… - … Heart, 2020 - openheart.bmj.com
… /valsartan might be beneficial in a wider population of patients with heart failure than the …
These new types of drugs are classified as angiotensin receptor blocker neprilysin inhibitors …

Effect of sacubitril-valsartan vs enalapril on aortic stiffness in patients with heart failure and reduced ejection fraction: a randomized clinical trial

AS Desai, SD Solomon, AM Shah, BL Claggett… - Jama, 2019 - jamanetwork.com
… for ACE inhibitors/angiotensin receptor blockers (ARBs) in patients with symptomatic HFrEF.
… was a multicenter randomized trial conducted at 85 hospital and clinic-based study sites in …