A randomized trial of vitamin D supplementation on vascular function in CKD
Vitamin D deficiency associates with mortality in patients with CKD, and vitamin D
supplementation might mitigate cardiovascular disease risk in CKD. In this randomized,
double-blind, placebo-controlled trial, we investigated the effect of cholecalciferol
supplementation on vascular function in 120 patients of either sex, aged 18–70 years, with
nondiabetic CKD stage 3–4 and vitamin D deficiency (serum 25-hydroxyvitamin D≤ 20
ng/ml). We randomized patients using a 1: 1 ratio to receive either two directly observed oral …
supplementation might mitigate cardiovascular disease risk in CKD. In this randomized,
double-blind, placebo-controlled trial, we investigated the effect of cholecalciferol
supplementation on vascular function in 120 patients of either sex, aged 18–70 years, with
nondiabetic CKD stage 3–4 and vitamin D deficiency (serum 25-hydroxyvitamin D≤ 20
ng/ml). We randomized patients using a 1: 1 ratio to receive either two directly observed oral …
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