Sperm Signaling Specificity: From Sperm Maturation to Oocyte Recognition

MJ Freitas, D Patrício, M Fardilha - Tissue-Specific Cell Signaling, 2020 - Springer
sperm motility and acrosome reaction as well as the unique … The cross-talk between both
signaling mechanisms is … thus leading to the prolonged exocytotic event that characterizes the …

The enigmatic sperm proteins in mammalian fertilization: an overview

GK Gahlay, N Rajput - Biology of Reproduction, 2020 - academic.oup.com
… Although the acrosome reaction is necessary for sperm to … progesterone release leading
to acrosome reaction [33, 34]. … PRSS55) is a GPI-anchored chymotrypsin like serine protease …

Capacitation-associated glycocomponents of mammalian sperm

M Liu - Reproductive sciences, 2016 - journals.sagepub.com
sperm surface are further processed for acrosome reaction … in this molecule leads to impaired
sperm function and subfertility. … CD59 is an 18 to 25 kDa GPI-anchored membrane protein

Site of mammalian sperm acrosome reaction

N Hirohashi - Sperm Acrosome Biogenesis and Function During …, 2016 - Springer
… surface before AR, which led us to rethink the actual sequence of events. … More recently,
Hyal5, another GPI-anchored hyaluronidase that localizes to both the sperm PM and the OAM, …

CD147 deficiency is associated with impaired sperm motility/acrosome reaction and offers a therapeutic target for asthenozoospermia

H Chen, X Shi, X Li, R Diao, Q Ma, J Jin, Z Qiu… - … Therapy-Nucleic Acids, 2021 - cell.com
… the acrosome reaction and improved the fertility of sperm from … sperm motility and acrosome
reaction (AR) by eliciting Ca 2+ … site of the acrosome reaction leading to fertilization in vitro. …

Sperm surface proteomics

IA Brewis, BM Gadella - … : Impact of immune reactions on human fertility, 2017 - Springer
… of the sperm head remains intact after the acrosome reaction and … enriched in GPI anchored
proteins and in proteins involved in … When immune responses are elicited towards the sperm

Protein markers of spermatogenesis and their potential use in the management of azoospermia

SC Araujo, RP Bertolla - Expert Review of Proteomics, 2021 - Taylor & Francis
… The differential expression of sperm proteins in patients with … , hyperactivation, acrosome
reaction, and fertilization processes … This protein is characterized as a GPI-anchored membrane …

Exogenous progesterone during in vitro fertilization improves developmental competence of partially cumulus-denuded bovine oocytes

MFS García, N Gabbanelli, GL Ríos, J Buschiazzo - Theriogenology, 2023 - Elsevier
Sperm undergoing acrosome reaction exhibited three … In mice, a sperm GPI-anchored protein
was found to be responsible for … to be able to detect a chemical guidance signal, leading to …

Comparative proteomic analysis of seminal plasma exosomes in buffalo with high and low sperm motility

K Yu, K Xiao, Q Sun, R Liu, L Huang, P Zhang, H Xu… - BMC genomics, 2023 - Springer
… To clarify the proteins contributing to sperm motility, … in regulating sperm maturation,
capacitation, acrosome reaction, … cells after removal from sperm, causing cumulus cells to elicit Ca-…

… acid type A receptor delta subunit (GABRD) and its interaction with purinergic P2X2 receptors in progesterone-induced acrosome reaction and male fertility

W Xu, K Wang, Y Chen, XT Liang, MK Yu… - Reproduction …, 2017 - CSIRO Publishing
… components of the GABA A receptor complex and the protein it interacts with to mediate
the progesterone-induced Ca 2+ influx that leads to the acrosome reaction in spermatozoa. …