… , as predictors of carrying BRCA1 or BRCA2 mutations specifically in ovarian cancer patients
of Asian … and the Myriad BRCA risk calculator in ovarian cancer patients of Korean ethnicity. …

… ovarian cancer (OC) predisposition genes, familial OC risk … new putative OC predisposition
genes based on germline … with a strong OC family history but without known BRCA1/2 …

… mutations in BRCA1 are believed to have a 57% lifetime risk of developing breast cancer,
while … The average risk of ovarian cancer in women with a BRCA1 mutation is 40% and with a …

… with the development of breast cancer (BC), ovarian cancer, and type J Fanconi anemia.
Based on recent work, we hypothesize that BRIP1 might be the gene involved in the onset of …

… 40 (including cancers identified at the time of risk-reducing surgery) but diagnosis before 40
is very rare in BRCA2 mutation carriers [10]. Mutations in other, non-BRCA OC genes in our …

… noting that breast cancer susceptibility gene 1 and 2 (BRCA1/2) … with hereditary breast
cancer. The data indicated that the … effect for the ovarian cancer patients with BRCA1/2 somatic …

… Breast cancer (BC) is the most commonly diagnosed cancer among women [1], while ovarian
cancer … BRCA1/2 were the first genes associated with hereditary BC and OC [3, 4]. Recently…

… Among the BC patients (Additional file 1), 54 were from unrelated BRCA1 and BRCA2-negative
families with elevated BC and/or ovarian cancer (OC) risk (ie families with two or more …

… Four BRCA1/2 non-coding regions were screened … breast and ovarian cancer predisposition
(3926 for BRCA1 and 3910 for BRCA2). The impact of a set of variants on BRCA1/2 gene …

… , as breast cancer and OC frequently present with inactivating mutations in BRCA1, the …
leads to stabilisation of the breast cancer susceptibility protein (BRCA) complex, and thus an …