… of most of the cytokine genes was markedly increased for up to 8 h, but then decreased over
… novel ChIL-23 complex that is more biologically active than p19 or p40 subunits alone, and …

… Interleukin (IL)-12 is a heterodimeric cytokine (p35/p40) involved … p19 and p35 subunits are
much more abundant than p40, … of bioactive IL-23 has also been detected in the rheumatoid …

… of p19 protein and/or formation of secreted bioactive IL-23, … formation between the IL-23p19
and IL-12p40 subunits in the … the expression of IL-23 in macrophages but inhibited IL-12 in …

… Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19)
and IL… as Schirmer I Test, break up time (BUT) and corneal fluorescent staining (CFS) (231). …

… IL23-specific p19 subunit with respect to distal blockade of IL-… , store, and release bioactive,
exogenous IL-17 [Citation18]. … abundant expression is observed in hematopoietic cells, but …

… binding affinity to IL-23 and bioactivity in whole blood. … anti-IL23 antibodies-treated groups
after subtraction of day 0 level. … Cell intercalation with natural abundance iridium was done …

… The p19 subunit is a 19K mw subunit that is linked by … Biologically active IL-23 requires both
subunits to be synthesized … There are a variety of gut pathogens that evoke a significant IL23 …

… pathogenesis of PsA is IL23. IL-23 is a heterodimer composed of two subunits p19 and p40
… Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in …

… cause a reduction in IL23 receptor activation-mediated … is due to lower levels of cell surface
receptor expression. For … and V362I variants have reduced protein stability. Finally, we …

… Considering the accumulating evidence on the pathogenic role of IL23, we generated
106 … expression of the interleukin (IL)23 subunit p19, but low levels of bioactive IL23 432 …