Activity of siderophores against drug-resistant Gram-positive and Gram-negative bacteria

K Gokarn, RB Pal - Infection and drug resistance, 2018 - Taylor & Francis
… Iron is acquired by microorganisms from the environment with the help of siderophores that
… Xenosiderophores (“Xeno” – not “self”) are exogenous siderophores, and when Fe 3 + ion is …

Iron acquisition systems of gram-negative bacterial pathogens define TonB-dependent pathways to novel antibiotics

PE Klebba, SMC Newton, DA Six, A Kumar… - Chemical …, 2021 - ACS Publications
Bacteria secrete siderophores that extract Fe 3+ from tissues, fluids, cells, and proteins; the
… the Gram-negative bacterial outer membrane actively acquire the resulting ferric siderophores

[HTML][HTML] Siderophores: Importance in bacterial pathogenesis and applications in medicine and industry

B Khasheii, P Mahmoodi, A Mohammadzadeh - Microbiological Research, 2021 - Elsevier
acquisition pathways in Gram-positive and -negative bacteria, importance of siderophore
production in pathogenesis of bacteria… ferric-siderophore complex in Gram-negative bacteria. …

The role of iron and siderophores in infection, and the development of siderophore antibiotics

MGP Page - Clinical Infectious Diseases, 2019 - academic.oup.com
… Ultimately, iron is acquired and transported into the bacterialSiderophore-conjugated
antibiotics that exploit such iron-… treatment of infections caused by gram-negative bacteria. Despite …

Targeting human pathogenic bacteria by siderophores: a proteomics review

D Ferreira, AML Seca, CGA Diana, AMS Silva - Journal of proteomics, 2016 - Elsevier
… human pathogenic Gram-negative bacteria and discuss the importance of siderophores in …
information about the siderophores iron acquisition of Gram-negative bacteria in the last three …

Production and uptake of distinct endogenous catecholate-type siderophores are required for iron acquisition and virulence in Chromobacterium violaceum

BB Batista, RERS Santos, R Ricci-Azevedo… - Infection and …, 2019 - Am Soc Microbiol
… , a siderophore produced by Escherichia coli and many other enteric bacteria, is an
archetypical catecholate-type siderophore … is a Gram-negative rod-shaped bacterium commonly …

A synthetic dual drug sideromycin induces Gram-negative bacteria to commit suicide with a Gram-positive antibiotic

R Liu, PA Miller, SB Vakulenko… - Journal of medicinal …, 2018 - ACS Publications
… to test our hypothesis related to siderophore-mediated dual drug delivery and β-… to
Gram-negative bacteria. The synthesis of 1 required access to all three components, the …

Siderophore-mediated iron acquisition and modulation of host-bacterial interactions

M Ellermann, JC Arthur - Free Radical Biology and Medicine, 2017 - Elsevier
… , and are synthesized and secreted by bacteria in order to scavenge iron when availability
is limited. In Gram-negative bacteria, siderophore-bound iron is transported through cognate …

[HTML][HTML] In vitro activity of the novel siderophore cephalosporin, cefiderocol, in Gram-negative pathogens in Europe by site of infection

FJ Candel, AS Henriksen, C Longshaw… - Clinical Microbiology …, 2022 - Elsevier
siderophore cephalosporin, cefiderocol and selected other antibacterial agents against
Gram-negative bacterial … A key resistance mechanism is acquisition of genes encoding …

Cefiderocol: a novel siderophore cephalosporin for multidrug-resistant Gram-negative bacterial infections

KA Parsels, KA Mastro, JM Steele… - Journal of …, 2021 - academic.oup.com
siderophore mechanism and potent in vitro activity against several Gram-negative bacteria,
it … iron-acquisition mechanism was utilized to enhance antibacterial penetration. Escherichia …