Adenosine receptor A2B negatively regulates cell migration in ovarian carcinoma cells

AR Campos-Contreras, A González-Gallardo… - International Journal of …, 2022 - mdpi.com
… the characterization of A2B receptor in particular cell lines. … activation of A2BR contributes
to ovarian cancer-derived cell … by cell proliferation, we evaluated if A2BR regulated cell viability…

A2B Adenosine Receptor and Cancer

ZG Gao, KA Jacobson - International journal of molecular sciences, 2019 - mdpi.com
activation of the P2Y 1 receptor (P2Y 1 R) subtype [1,2], whereas adenosine induces cancer
cell proliferation and growth … -small cell lung cancer, breast cancer and ovarian cancer. A 2B …

Adenosine receptor A2b confers ovarian cancer survival and PARP inhibitor resistance through IL‐6‐STAT3 signalling

L Chi, L Huan, C Zhang, H Wang… - Journal of Cellular and …, 2023 - Wiley Online Library
… in ovarian cancer cells, we examined the cell growth and … signalling regulates cell survival
and proliferation by activating … upregulated A 2B senses adenosine signal and activates IL-6…

Role of adenosine A2b receptor overexpression in tumor progression

C Sepúlveda, I Palomo, E Fuentes - Life sciences, 2016 - Elsevier
… In addition A2b can link to the Gq protein triggering the activationA2b receptor is the
adenosine receptor with the lowest affinity for … and 17 primary cultures of malignant ovarian tumor. …

Adenosine enhances cisplatin sensitivity in human ovarian cancer cells

P Sureechatchaiyan, A Hamacher, N Brockmann… - Purinergic …, 2018 - Springer
… signaling for inhibition of cancer cell growth and proliferation. … by activation of A2B receptors
[34, 37] or A1 receptors [38], both adenosine receptors activated in our ovarian cancer cell

[HTML][HTML] Role of adenosine in tumor progression: focus on A2B receptor as potential therapeutic target

C Sorrentino, S Morello - … of Cancer Metastasis and Treatment, 2017 - oaepublish.com
… analog NECA induces apoptosis in ovarian cancer cells. [114] … A 2B adenosine receptor in
some cancer cell types promotes … between A2B adenosine receptors and hypoxia in activating

A2B adenosine receptor agonist induces cell cycle arrest and apoptosis in breast cancer stem cells via ERK1/2 phosphorylation

SM Jafari, HR Joshaghani, M Panjehpour, M Aghaei - Cellular Oncology, 2018 - Springer
… -regulated ERK1/2 phosphorylation in the breast cancer cell … Since caspase cascade activation
plays a key role in … can induce apoptosis in colon and ovarian cancer cells [31, 32]. Mittal …

Adenosine: an endogenous mediator in the pathogenesis of gynecological cancer

A Bahreyni, SS Samani, E Ghorbani… - Journal of Cellular …, 2018 - Wiley Online Library
Activation of A2b adenosine receptor increases proliferation … A3 adenosine receptor can
regulate both cell proliferation … the role of A2b adenosine receptor signaling in ovarian cancer

[HTML][HTML] Blockade of adenosine A2b receptor reduces tumor growth and migration in renal cell carcinoma

Y Yi, Y Zhou, X Chu, X Zheng, D Fei, J Lei, H Qi… - … of Cancer, 2020 - ncbi.nlm.nih.gov
… , prostate, ovarian carcinoma, adenosine A2b receptor is … adenosine receptors, which suggests
that it may play a role in … CREB activation by PKA, thereby increasing cell proliferation 31 …

Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages–a self-amplifying …

I Montalbán del Barrio, C Penski, L Schlahsa… - … of cancer, 2016 - Springer
… T cell proliferation was determined on a FACSCalibur flow … less in response to activation of
the A3 adenosine receptor [69]. … of adenosine receptors A1, A2A, A2B and A3, the analysis of …