Preventing germ cell death by inactivating aryl hydrocarbon receptor (AHR)
P Esakky, KH Moley - Cell Death & Disease, 2016 - nature.com
… Tobacco causes nearly six million deaths per year worldwide; in the US, smoking and
second-hand smoke … , Ahr knockdown did not reduce CSC-mediated caspase activation or plasma …
second-hand smoke … , Ahr knockdown did not reduce CSC-mediated caspase activation or plasma …
The role of the aryl hydrocarbon receptor (AHR) in immune and inflammatory diseases
DR Neavin, D Liu, B Ray… - International journal of …, 2018 - mdpi.com
… and the expression of AHR target genes are lower in germ-free mice [10] and … smoke, which
indicates that there is a potential interaction between cigarette smoke and AHR activation in …
indicates that there is a potential interaction between cigarette smoke and AHR activation in …
Aryl hydrocarbon receptor ligands in cigarette smoke induce production of interleukin-22 to promote pancreatic fibrosis in models of chronic pancreatitis
J Xue, Q Zhao, V Sharma, LP Nguyen, YN Lee… - Gastroenterology, 2016 - Elsevier
… Biotec, Bergisch Gladbach, Germany) or vehicle control was … of cigarette smoke AhR ligands
on immune activation and on … in cigarette smoke, we tested the effect of combined lower …
on immune activation and on … in cigarette smoke, we tested the effect of combined lower …
Paternal smoking and germ cell death: A mechanistic link to the effects of cigarette smoke on spermatogenesis and possible long-term sequelae in offspring
P Esakky, KH Moley - Molecular and cellular endocrinology, 2016 - Elsevier
… Activation of AHR by growth factors though benefits normal … even though the sperm numbers
were found decreased in … Aryl hydrocarbon receptor gene silencing with small inhibitory …
were found decreased in … Aryl hydrocarbon receptor gene silencing with small inhibitory …
Antioxidant functions of the aryl hydrocarbon receptor
C Dietrich - Stem cells international, 2016 - Wiley Online Library
… nuclear translocator (ARNT) and transcriptional activation of several xenobiotic phase I and
… and show decreased upregulation of NQO1 and Srxn in response to cigarette smoke extract […
… and show decreased upregulation of NQO1 and Srxn in response to cigarette smoke extract […
Smoking-induced aggravation of experimental arthritis is dependent of aryl hydrocarbon receptor activation in Th17 cells
J Talbot, RS Peres, LG Pinto, RDR Oliveira… - Arthritis Research & …, 2018 - Springer
… cigarette smoke [21, 22]. We hypothesized that AHR activation by cigarette smoke components
… AhR activity, reducing the background for the assay of AhR activation and consequently …
… AhR activity, reducing the background for the assay of AhR activation and consequently …
The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease
V Rothhammer, FJ Quintana - Nature Reviews Immunology, 2019 - nature.com
… Of note, indoxyl-3-sulfate is absent from the circulation of germ-… Similarly, AHR activation by
agonists in cigarette smoke … the expense of a decreased ability to activate effector T cells 125 …
agonists in cigarette smoke … the expense of a decreased ability to activate effector T cells 125 …
Aryl hydrocarbon receptor (AhR)-dependent regulation of pulmonary miRNA by chronic cigarette smoke exposure
S Rogers, AR de Souza, M Zago, M Iu, N Guerrina… - Scientific reports, 2017 - nature.com
… The aryl hydrocarbon receptor (AhR) is a ligand-activated … There is a significant decrease
in Srxn1 in COPD 31 , a … -Gurr Stain (Merck, Darmstadt, Germany). Lung tissue was collected …
in Srxn1 in COPD 31 , a … -Gurr Stain (Merck, Darmstadt, Germany). Lung tissue was collected …
A promoter variant within the aryl hydrocarbon receptor gene is associated with an epithelial barrier defect in smokers with Crohn's disease
M Prager, J Büttner, P Grunert… - Inflammatory Bowel …, 2016 - academic.oup.com
… Patients were recruited from the Charité University Hospital (Berlin, Germany). Diagnosis of
… showed a decrease of IP with cigarette consumption. In healthy subjects, cigarette smoke did …
… showed a decrease of IP with cigarette consumption. In healthy subjects, cigarette smoke did …
… regulation of p23 in normal lung epithelial cells reduces toxicities from exposure to benzo [a] pyrene and cigarette smoke condensate via an aryl hydrocarbon receptor …
J Chen, P Yakkundi, WK Chan - Toxicological Sciences, 2019 - academic.oup.com
… The aryl hydrocarbon receptor (AHR) is a ligand-activated signaling molecule which
controls tumor growth and metastasis, T cell differentiation, and liver development. Expression …
controls tumor growth and metastasis, T cell differentiation, and liver development. Expression …