… t(8;21)(q22;q22) acute myelogenous leukemia (AML) is morphologically characterized by a
… heterogeneous leukemia cells from myeloblasts to differentiated myeloid elements. Thus, t(8;…

… in AML is the t(8;21)(q22;q22) translocation, first described … translocation is that the AML1
gene (Acute Myeloid Leukemia… (Eight-Twenty-One) gene located on the long arm of the 8th …

Background Although the prognosis of core‐binding factor ( CBF ) acute myeloid leukemia (
AML ) is better than other subtypes of AML , 30% of patients still relapse and may require …

… Acute myeloid leukemia (AML) is caused by genetic alterations that lead to enhanced … ,
translocations, and gene mutations. The most frequently found translocations/inversions are t(8;21…

… Prognostic factors and outcome of core binding factor acute myeloid leukemia patients
with t(8;21) differ from those with inv(16): a Cancer and Leukemia Group B study. J Clin Oncol …

… acute myeloid leukemia (AML) is broad and heterogeneous when compared to … myeloid
leukemia and other myeloid neoplasms. Recurrent chromosomal translocations such as t(8;21), t…

… CD19 as an immunophenotypic marker was at a relatively high frequency (50%) in cases
with t (8; 21), and patients with this translocation had a specific immunophenotypic pattern of …

… inform risk stratification in pediatric acute myeloid leukemia (AML). We describe the first
case of a newborn with leukemia cutis found to have AML harboring a cryptic insertional t(8;16)(…

… protein is essential to the development of t(8;21) acute myeloid leukemia (AML) and is well
… wild-type AML1 remains elusive in the leukemogenesis of t(8;21) AML. Through chromatin …

… Although a genetic basis for morphologic and transcriptional differences between t(8;21) …
specifically in t(8;21) AML patients. ASXL1/2 mutations have been described in ∼35% of t(8;21) …