Proteomics as a tool for studying bacterial virulence and antimicrobial resistance

FJ Pérez-Llarena, G Bou - Frontiers in microbiology, 2016 - frontiersin.org
… Two other rarely observed types of acquired resistance … baumannii strains assigned to
international clone 2, which is … cenocepacia, particularly in regard to bacterial adaptation to …

Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation

RH Little, L Grenga, G Saalbach, AM Howat… - … genetics, 2016 - journals.plos.org
… To this end, we cloned and purified an allele of SBW25 RpsF with the penultimate C-… We
then tested the RpsF-D139K variant for glutamation by both SBW25 and E. coli RimK, and …

Gene expression variability in clonal populations: causes and consequences

S Roberfroid, J Vanderleyden… - Critical reviews in …, 2016 - Taylor & Francis
Clonal populations can be very diverse: eg a single bacterial … and proteomics studies.
However, as mentioned above, … the advantage of fast adaptation to changing conditions in …

Two FtsH Proteases Contribute to Fitness and Adaptation of Pseudomonas aeruginosa Clone C Strains

SM Kamal, ML Rybtke, M Nimtz, S Sperlein… - Frontiers in …, 2019 - frontiersin.org
bacterium and a nosocomial pathogen with clone C one of the most prevalent clonal groups…
To construct catalytically inactive FtsH protease variants for substrate trapping, ftsH1 and …

Targeting human pathogenic bacteria by siderophores: a proteomics review

D Ferreira, AML Seca, CGA Diana, AMS Silva - Journal of proteomics, 2016 - Elsevier
… the types of siderophores produced by microbes and their role … utility in exhibiting the
adaptation mechanisms of pathogens … was retrieved different clinical clones in three different …

Proteomic Investigation of Tolerant Escherichia coli Populations from Cyclic Antibiotic Treatment

JE Sulaiman, H Lam - Journal of proteome research, 2020 - ACS Publications
… simulate how bacteria in their … adaptation strategy to counteract the specific type of antibiotic
(41) used during the cyclic ALE experiment, and therefore unable to survive other types of …

Deciphering multifactorial resistance phenotypes in Acinetobacter baumannii by genomics and targeted label-free proteomics

T Cecchini, EJ Yoon, Y Charretier, C Bardet… - … & Cellular Proteomics, 2018 - ASBMB
… normalized using “bacterial quantotypic peptides,” ie peptide markers of the bacterial quantity,
to obtain precise protein quantitation (on average 8.93% coefficient of variation for three …

[HTML][HTML] From the genome sequence via the proteome to cell physiology–Pathoproteomics and pathophysiology of Staphylococcus aureus

M Hecker, U Mäder, U Völker - International Journal of Medical …, 2018 - Elsevier
… These new insights into bacterial adaptation are starting points for detailed follow-up …
Importantly, murine and human monoclonal antibodies targeting IsaA, the latter cloned directly from …

Polygenic Adaptation and Clonal Interference Enable Sustained Diversity in Experimental Pseudomonas aeruginosa Populations

KB Harris, KM Flynn, VS Cooper - Molecular Biology and …, 2021 - academic.oup.com
Bacteria that attach to a polystyrene bead are transferred … We hypothesized that this media
may select different adaptive … , indicating much greater genetic variation at frequencies below …

Insertion sequences drive the emergence of a highly adapted human pathogen

E Sentausa, P Basso, A Berry, A Adrait… - Microbial …, 2020 - microbiologyresearch.org
… the extent of evolutionary adaptation during the course of … ) and at least one of the proteomics
datasets. The protein subcellular … with CLJ1_1187 contributed to bacterial adaptation to in-…