Behavioral changes induced through adenosine A2A receptor ligands in a rat depression model induced by olfactory bulbectomy
KM Padilla, A Quintanar‐Setephano… - Brain and …, 2018 - Wiley Online Library
… of chronic depression by means of brain surgery. Adenosine purinergic receptors A2A (…
This study aimed to show which A2A receptor ligands exert antidepressive-like effects in the …
This study aimed to show which A2A receptor ligands exert antidepressive-like effects in the …
The role of adenosine receptors in mood and anxiety disorders
D van Calker, K Biber, K Domschke… - Journal of …, 2019 - Wiley Online Library
… Activation of A 2A receptors is associated with increased depression-like symptoms, while
… Interaction between adenosine A1 and A2A receptors in the regulation of depressive-like …
… Interaction between adenosine A1 and A2A receptors in the regulation of depressive-like …
Purinergic system and suicidal behavior: exploring the link between adenosine A2A receptors and depressive/impulsive features
… First, it has been shown that adenosine may induce “depressant” effects in animal models, …
adenosine A2A receptors may reverse these effects [4]. Consistently, adenosine A2A receptor …
adenosine A2A receptors may reverse these effects [4]. Consistently, adenosine A2A receptor …
[HTML][HTML] Can adenosine A2A receptor antagonists be used to treat cognitive impairment, depression or excessive sleepiness in Parkinson's disease?
P Jenner, A Mori, T Kanda - Parkinsonism & Related Disorders, 2020 - Elsevier
… of the motivational symptoms of depression, which may relate to the apathetic/anhedonic
expression of depression that can occur in PD. Adenosine and A 2A receptors play a prominent …
expression of depression that can occur in PD. Adenosine and A 2A receptors play a prominent …
[HTML][HTML] Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula
M Wang, P Li, Z Li, BS da Silva, W Zheng… - Nature …, 2023 - nature.com
… The lateral septum (LS) is thought to control of depression, however, the cellular and circuit
… of LS GABAergic adenosine A 2A receptors (A 2A R)-positive neurons mediating depressive …
… of LS GABAergic adenosine A 2A receptors (A 2A R)-positive neurons mediating depressive …
Adenosine A2A receptor as potential therapeutic target in neuropsychiatric disorders
MR Domenici, A Ferrante, A Martire, V Chiodi… - Pharmacological …, 2019 - Elsevier
Adenosine A 2A receptor (A 2A R) is a G-protein coupled receptor that regulates several
important functions in the central nervous system. Large amount of preclinical data suggests …
important functions in the central nervous system. Large amount of preclinical data suggests …
[HTML][HTML] Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome
A Moreira-de-Sá, FQ Gonçalves, JP Lopes… - Neurobiology of …, 2020 - Elsevier
… Adenosine A 2A receptors format long-term depression and … Since adenosine A 2A receptors
(A 2A R) are powerful … with a decreased magnitude of long-term depression (LTD) in CA1 …
(A 2A R) are powerful … with a decreased magnitude of long-term depression (LTD) in CA1 …
Early-life hyperthermic seizures upregulate adenosine A2A receptors in the cortex and promote depressive-like behavior in adult rats
M Crespo, DA León-Navarro, M Martín - Epilepsy & Behavior, 2018 - Elsevier
… depression. Finally, animals were sacrificed 56 days after hyperthermia-induced seizures
(HIS), and their effects on adenosine A 2A receptor … Adenosine A2A receptors and depression …
(HIS), and their effects on adenosine A 2A receptor … Adenosine A2A receptors and depression …
Ketamine counteracts sevoflurane-induced depressive-like behavior and synaptic plasticity impairments through the adenosine A2A receptor/ERK pathway in rats
W Yu, Z Wu, X Li, M Ding, Y Xu, P Zhao - Molecular Neurobiology, 2023 - Springer
… Adenosine, an inhibitory neurotransmitter, fine-tunes hippocampal synaptic plasticity [20].
The role of the adenosine A2A receptor … , its involvement in depression and antidepressant …
The role of the adenosine A2A receptor … , its involvement in depression and antidepressant …
Molecular and Structural Insight into Adenosine A2A Receptor in Neurodegenerative Disorders: A Significant Target for Efficient Treatment Approach
… of the receptor (46). Based on convergent and extensive experimental data, the A2A receptor
… Adenosine levels rising and the emergence of depression in animal models are correlated, …
… Adenosine levels rising and the emergence of depression in animal models are correlated, …
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