… by deamination catalyzed by adenosine deaminase (or adenosine aminohydrolase) [EC 3.5.…
This is the result of the bulky azido group of AZTMP which sterically prevents the movement …

… 6-deoxy-2-aminopurine derivatives (eg famciclovir), which … high immunogenicity of conjugates
preventing the repetition of … The use viral vectors (eg adenoviruses, retroviruses, lentivirus…

… 2-aminopurine (2AP… inhibitors that could serve as potential drug candidates. DNA repair
pathways are often upregulated in tumor cells treated with DNA-damaging agents and inhibition …

… diseases can be treated by potent, selective inhibitors of hu… considered as selective ligands
for adenosine receptors, showing … [194], who utilized 2-aminopurine residue as a fluorescent …

… Nuclei from the KD cells indicated treated or not with Dox for 6 days were … Treating multiH1sh
cells with 2-aminopurine, an inhibitor of IFN-inducible dsRNA-activated protein kinase R (…

… that tyrosine kinase inhibitors can reduce or prevent the … and inhibited assembly by mixes of
drug-sensitive and drug-… and liver HBV load in the adenovirus mouse model. Treatment with …

… drug in novel antibiotics. They block the active sites of viral/bacterial active sites and terminate
their protein synthesis … anticancer agentsare the agents which prevent cancer cells to …

… the number of nucleoside-based drugs is steadily increasing. Antiviral … prevent the viral
penetration of the cell membrane or the subsequent replication of the virus inside the host cell.[43…

… Furthermore, in a case report of an ovarian cancer patient treated with an oncolytic adenovirus
encoding hGM-CSF (ONCOS-102), progressive infiltration of CD8+ T cells in the tumor …

… FIGURE 3Processive elongation and single nucleotide incorporation measured by
stopped-flow 2-aminopurine fluorescence. A, hairpin primer-template RNA on which preinitiated …