… 2j), consistent with an increased proportion of R cells in the final composition of clones
with … We show that (1) NSCs show reduced proliferative activity with age, causing reduced …

… structure by histone post-translational modifications (more particularly, histone acetylation)
and DNA methylation. In the nucleus of the cell, … of resveratrol stimulate cell proliferation, high …

… hippocampal circuitry reveals an age-dependent decrease in excitatory postsynaptic potential…
with age and how changes in cytoskeletal structure or ECM composition may play a role in …

… To this aim, changes in the cellular composition of the dentate … Studies on rodents showed
a correlation between age-dependent … Afterwards, proliferation progressively declines, and we …

… born cells in the dentate gyrus of the hippocampal formation. … decline in cellular proliferation
in this structure that occurs at … cellular proliferation and neurogenesis in the hippocampal …

… The granule cell (GC) layer is the information gateway to the HC and exhibits an age-dependent
decrease in activity that might impact directly on memory encoding. Input signals …

… their cytoplasmic structure, such as deramified/atrophic cells (solid … with the previously
reported age-dependent decline in … First, the effect of aging on the proliferation in hippocampus is …

… We confirmed that, as predicted, these cells were non-proliferative by injecting 12 month
old mice with ethynyldeoxyuridine (EdU) and analyzing SA-β-Gal and EdU 24 h later. No SA-β-…

… Age-dependent changes in proliferative astrocyte response to the stab wound injury of the
GM. (A) Stab wound injury of the somatosensory GM induced a broad expression of GFAP in …

… age-dependent epigenetic erosion. To probe for the involvement of aging, we generated
rejuvenated iPSC-derived neurons … neuronal changes as age-dependent cellular programs that …