The relationship between the striatal dopaminergic neuronal and cognitive function with aging

H Li, S Hirano, S Furukawa, Y Nakano… - Frontiers in aging …, 2020 - frontiersin.org
… among age-related changes in the striatal dopamine … as depression, autonomic dysfunction,
and cognitive impairment. … that the age-related decline of striatal dopamine was influenced …

[HTML][HTML] Age-related changes in the metabolic profiles of rat hippocampus, medial prefrontal cortex and striatum

LW Durani, HS Hamezah, NF Ibrahim… - Biochemical and …, 2017 - Elsevier
… mechanisms underlying age-related cognitive impairments. Thus, it is … Data were submitted
to Pareto scaling to decrease the … to the golgi complex to produce complex sphingolipids like …

Female rats are resistant to cognitive, motor and dopaminergic deficits in the reserpine-induced progressive model of Parkinson's disease

AC Lima, YSR Meurer, VS Bioni… - Frontiers in aging …, 2021 - frontiersin.org
cognitive deficits in male rats. The behavioral effects of reserpine were attenuated (motor) or
absent (cognitive… -treated rats, irrespective of sex, presented a significant decrease in motor …

[HTML][HTML] Volumetric changes in the aging rat brain and its impact on cognitive and locomotor functions

HS Hamezah, LW Durani, NF Ibrahim… - Experimental …, 2017 - Elsevier
… , age-related increases in oxidative stress, impairment in … age-dependent decrease in the
volume of the mPFC, striatum, and … locomotor and cognitive deficits in aging. The most marked …

Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender …

…, A Swomley, DK Powell, DA Butterfield - Free Radical Biology …, 2019 - Elsevier
… Distinct gender- and age-related alterations were found. The … , in late-stage of PD, cognitive
deficits are observed [2]. Anosmia … plexus is where CSF is produced. CSF circulates up and …

Effects of aging on executive functioning and mesocorticolimbic dopamine markers in male Fischer 344× brown Norway rats

RJ Tomm, TT Maric, DJ Tobiansky, HR Schweitzer… - Neurobiology of …, 2018 - Elsevier
… suggest that age-related decrements in cognitive flexibility … reductions in markers for DA
activity, it was of interest to assess differences in these markers between young and aged rats

Aging-associated cognitive decline is reversed by D-serine supplementation

L Nava-Gómez, I Calero-Vargas, F Higinio-Rodríguez… - Eneuro, 2022 - eneuro.org
… supplementation reverts the age-related decline in cognitive flexibility, … atlas, and the striatum
was selected from the WHS atlas. … makes functional brain connectivity relevant for cognitive

Impact of aging on the 6-OHDA-induced rat model of Parkinson's disease

S Barata-Antunes, FG Teixeira… - International journal of …, 2020 - mdpi.com
… (SNpc) and the consequent decline of the striatal DA content [2]. … of DA neurons, where it
generates mitochondrial respiratory … Age-related differences in post-surgery recovery were also …

Initiation of calorie restriction in middle-aged male rats attenuates aging-related motoric decline and bradykinesia without increased striatal dopamine

MF Salvatore, J Terrebonne, V Fields, D Nodurft… - Neurobiology of …, 2016 - Elsevier
… that age-related decreases in striatal DA do not meet, let alone exceed, the threshold of striatal
DA loss … To this end, it would be now critical to evaluate if CR would still produce a similar …

Effect of Paullinia cupana Mart. Commercial Extract During the Aging of Middle Age Wistar Rats: Differential Effects on the Hippocampus and Striatum

MR Mingori, L Heimfarth, CF Ferreira, HM Gomes… - Neurochemical …, 2017 - Springer
… /oxidant balance, which causes oxidative damage. The effects of … of age-related disorders
that cause cognitive and motor … We observed a decrease in the number of striatum GFAP-…