… primary non-transformed human lung fibroblasts. These cells … plateaus up to 0.5 Gy, with
evidence for a further increase at 1 … that the induction of sister chromatid exchanges in CHO and …

… quantification of nuclear alpha particle-induced DNA damage … The solid cancer dose
response derived from is evidence in … in failure to separate sister chromatids, mitotic catastrophe …

… Using biology and biochemistry, I present evidence that supports the hypothesis that SNM1C
functions to resolve DNA interstrand crosslink clustered together with DNA double strand …

… The evidence of GI induced from radiation exposures has been … , this one DNA chromosome
is replicated in the S phase of the cell cycle--which duplicates two sister chromatids that are …

… is challenged by the accumulating evidence of experimental non-… It was speculated to be
infinity using sister chromatid exchanges … working on alpha particle induced bystander effects. …

… Sister chromatid exchanges SDS … , the induction of RIGI in normal primary human fibroblast
(HF19) cells was … instability and the deficiency of sharp proof of participation of DNA double-…

… senescent human fibroblasts and mouse embryonic fibroblasts (MEFs) … from normal, healthy
individuals and did not find evidence of … Telomere loss results in sister chromatid fusion and …

… Empirical evidence across KERs can support construction of quantified AOPs (qAOPs).
Using an example AOP of energy deposition from ionizing radiation onto DNA leading to lung …

… studies have provided enough evidence to conclude that … around 90% of alpha-particle-induced
damage was repaired [79… lung fibroblast cell line V-79 together with lung fibroblasts from …

… demonstrated increases in sister chromatid exchanges (SCEs) … apoptotic cell death of normal
human fibroblasts exposed to low … Normal human skin fibroblasts used in this study were …