Tight junctions in the development of asthma, chronic rhinosinusitis, atopic dermatitis, eosinophilic esophagitis, and inflammatory bowel diseases
K Sugita, K Kabashima - Journal of leukocyte biology, 2020 - academic.oup.com
… that bronchial epithelial barrier leakiness in asthmatic … function by increasing the TJ
expression. In lung and normal bronchial epithelial cells, there are commonly expressed junctional …
expression. In lung and normal bronchial epithelial cells, there are commonly expressed junctional …
Role of airway epithelial barrier dysfunction in pathogenesis of asthma
Y Gon, S Hashimoto - Allergology International, 2018 - jstage.jst.go.jp
… onset of allergic inflammation, disrupts the tight junction directly … A study of the tight junction
proteins in airway epithelial cells … , suggesting the potential involvement of EGFR signaling. …
proteins in airway epithelial cells … , suggesting the potential involvement of EGFR signaling. …
The role of defective epithelial barriers in allergic lung disease and asthma development
N Noureddine, M Chalubinski… - Journal of asthma and …, 2022 - Taylor & Francis
… epithelial barrier and result in the chronic inflammation seen in allergic diseases and asthma…
Citation20 Gap junction proteins (GJs), connexins, which are expressed in different types of …
Citation20 Gap junction proteins (GJs), connexins, which are expressed in different types of …
Epithelial barriers in allergy and asthma
PW Hellings, B Steelant - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
… 2 inflammatory responses often seen in allergic asthma and … , AR, or COPD suggest a
possible role for different HDACs in … barrier function and junctional proteins in primary bronchial …
possible role for different HDACs in … barrier function and junctional proteins in primary bronchial …
Epithelial cell dysfunction, a major driver of asthma development
IH Heijink, VNS Kuchibhotla, MP Roffel, T Maes… - Allergy, 2020 - Wiley Online Library
… with delocalization of junctional proteins (Figure 3). … inflammation associated with atopic
asthma. Both Th2 cells and ILC2 may contribute to the compromised epithelial barrier function …
asthma. Both Th2 cells and ILC2 may contribute to the compromised epithelial barrier function …
Tight junction, mucin, and inflammasome‐related molecules are differentially expressed in eosinophilic, mixed, and neutrophilic experimental asthma in mice
… epithelial tight junction (TJ) molecules’ expression and barrier function are impaired in asthma
… Our finding of significantly downregulated Zo-1 in all inflammatory phenotypes of AAI is in …
… Our finding of significantly downregulated Zo-1 in all inflammatory phenotypes of AAI is in …
[HTML][HTML] Phenotypic and genetic aspects of epithelial barrier function in asthmatic patients
… junctional proteins is likely to have important implications for the maintenance and stability
of the epithelium … severe asthma than type 2 inflammation, suggesting that epithelial integrity …
of the epithelium … severe asthma than type 2 inflammation, suggesting that epithelial integrity …
Tight junctions in pulmonary epithelia during lung inflammation
OH Wittekindt - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
… Inflammatory lung diseases like asthma bronchiale, chronic obstructive pulmonary …
inflammation is elusive. This review emphasises the role of the tight junction of the airway epithelium …
inflammation is elusive. This review emphasises the role of the tight junction of the airway epithelium …
Mucosal barrier defects: what have we learned from atopic dermatitis, asthma, and allergic rhinitis?
… roles for tight junction proteins in the … allergic inflammatory mediators driving epithelial
barrier dysfunction in AR. In addition, this study describes the epithelial barrier and TJ proteins in …
barrier dysfunction in AR. In addition, this study describes the epithelial barrier and TJ proteins in …
Mechanisms and biomarkers of airway epithelial cell damage in asthma: A review
Y Yang, M Jia, Y Ou, IM Adcock… - The Clinical Respiratory …, 2021 - Wiley Online Library
… pathological changes in severe asthma due, in part, to activation of inflammatory and immune
… and IL-6 gene expression. Other miRNAs expressed in AEC with a potential role in asthma …
… and IL-6 gene expression. Other miRNAs expressed in AEC with a potential role in asthma …