Alzheimer's disease–the 'microbial hypothesis' from a clinical and neuroimaging perspective

L Frölich - Psychiatry Research: Neuroimaging, 2020 - Elsevier
… The etiology of Alzheimer's disease (AD) is under debate since its first description in 1906.
Extracellular senile plaques composed of beta-amyloid peptide (Aβ) and intracellular …

Combined creutzfeldt-jakob/Alzheimer's disease cases are important in search for microbes in Alzheimer's disease

FO Bastian - Journal of Alzheimer's Disease, 2017 - content.iospress.com
… The question whether Alzheimer’s disease is infectious as brought up in the recent editorial
published in the Journal of Alzheimer’s Disease is complicated by the controversy whether …

The Historical Development of the Pathological Changes in Alzheimer's Disease Based on Microbiology, Anatomy, and Physiology

HB Allen, RA Allen - Medical Research Archives, 2022 - esmed.org
… Miklossy in her salient paper documenting ALZ as an infection by the Koch/Hill criteria5. …
Alzheimer’s DiseaseA Neurospirochetosis. Analysis of the evidence following Koch’s and Hill’…

[PDF][PDF] Alzheimer's disease: A novel hypothesis integrating spirochetes, biofilm, and the immune system

HB Allen, D Morales, K Jones, S Joshi - J Neuroinfect Dis, 2016 - academia.edu
In the light of recent studies showing the presence of spirochetes in the brains of Alzheimer’s
disease (AD) patients, we have studied (post mortem) the hippocampus region in the …

[HTML][HTML] A novel approach to the treatment and prevention of Alzheimer's disease based on the pathology and microbiology

HB Allen - Journal of Alzheimer's Disease, 2021 - content.iospress.com
… The pathology stains included for study of these postmortem, fixed tissue, Alzheimer’s disease
(… This includes the recent report on Lewy body dementia where BB were still present after

[PDF][PDF] Alzheimer's disease: The novel finding of intracellular biofilms

HB Allen, R Allawh, A Touati, C Katsetos… - J Neuroinfect …, 2017 - researchgate.net
… Treating after the biofilms have formed is much more challenging. A biofilm dispersing … the
debris needs to be cleared from the brain after the biofilm is dispersed and the organisms are …

[HTML][HTML] Risk of dementia in patients with leptospirosis: a nationwide cohort analysis

CH Chiu, PC Chen, YC Wang, CL Lin, FY Lee… - International Journal of …, 2019 - mdpi.com
… that enable researchers to trace the details of participants throughout the follow-up period
of the study. The present study had several limitations that must be considered. First, the …

[图书][B] Explicating the relationship between Infections and Alzheimer's Disease (AD) Etiology, especially Late-onset AD (LOAD).

HK Saboowala - 2020 - books.google.com
Alzheimer’s disease - a neurospirochetosis. Analysis of the evidence following Koch’s and
Hill’… Herpes simplex infection and the risk of Alzheimer’s disease: A nested case-control study. …

[PDF][PDF] The essential role of biofilms in Alzheimer's disease

HB Allen - Microbiol Infect Dis, 2019 - researchgate.net
… Next came analysis by the Koch/Hill postulates which showed AD to be infectious and …
Alzheimer’s Disease-A Neurospirochetosis. Analysis of the Evidence following Koch’s and Hill

[PDF][PDF] Alzheimer's disease: Possible mechanisms for worsening of the disease

HB Allen, RM Allawh, EN Ilyas, J Miklossy… - Curr …, 2018 - researchgate.net
… shown to cause worsening of Alzheimer’s disease (AD). In the following, we outline a possible
… adaptive immune system (lymphocytes and IgG) after disruption of the blood brain barrier. …