[HTML][HTML] Potential roles of amiloride-sensitive sodium channels in cancer development
S Xu, C Liu, Y Ma, HL Ji, X Li - BioMed research international, 2016 - hindawi.com
… Increasing evidence suggests that ion channels not only regulate ion … “Relative contribution
of chloride channels and transporters to regulatory volume decrease in human glioma cells,” …
of chloride channels and transporters to regulatory volume decrease in human glioma cells,” …
Ion channels and their role in the pathophysiology of gliomas
T Takayasu, K Kurisu, Y Esquenazi… - Molecular cancer …, 2020 - AACR
… Cell volume changes through the regulation of ion flux, … increased understanding of the
contributions of ion channels … form an amiloride-sensitive nonselective cation channel. The …
contributions of ion channels … form an amiloride-sensitive nonselective cation channel. The …
[HTML][HTML] Ion channels as therapeutic targets in high grade gliomas
M Griffin, R Khan, S Basu, S Smith - Cancers, 2020 - mdpi.com
… sodium channels (ENaC) are a class of amiloride-sensitive … of human glioma biopsies found
that higher grade gliomas … in glioma cell division, likely because of its regulatory effect on …
that higher grade gliomas … in glioma cell division, likely because of its regulatory effect on …
[HTML][HTML] Ion channels in gliomas—from molecular basis to treatment
AF Elias, BC Lin, BJ Piggott - International Journal of Molecular Sciences, 2023 - mdpi.com
… for ASIC1 in glioma cell volume regulation in response to a … at the invadopodium of D54
human glioma cells [16,17]. Blocking … to form an amiloride-sensitive nonselective cation channel. …
human glioma cells [16,17]. Blocking … to form an amiloride-sensitive nonselective cation channel. …
[HTML][HTML] ENaC/DEG in tumor development and progression
… -grade human malignant glioma, immortalized human glioma cells … , or sodium 4-phenylbutyrate,
a transcriptional regulator, … of the amiloride-sensitive channel activity may reverse high-…
a transcriptional regulator, … of the amiloride-sensitive channel activity may reverse high-…
[PDF][PDF] Gliomas malignos expressam canais de Na+ sensíveis ao amiloride
JK Bubien, DA Keeton, CM Fuller, GY Gillespie… - medicinacomplementar.com.br
… cell lines originally derived from human glioblastoma cells (… presence of amiloride-sensitive
inward Na+ currents in human … regulated ion channels; such channels may be involved in …
inward Na+ currents in human … regulated ion channels; such channels may be involved in …
[HTML][HTML] Mambalgin-2 induces cell cycle arrest and apoptosis in glioma cells via interaction with ASIC1a
… can participate in the regulation of glioblastoma cell … the amiloride-sensitive ASIC1a channels
in glioma U251 MG … Our data suggest that mambalgin-2 inhibits the growth of glioma cells …
in glioma U251 MG … Our data suggest that mambalgin-2 inhibits the growth of glioma cells …
Sodium homeostasis in the tumour microenvironment
… to metabolism, pH regulation, vascularity and cell density that … that increases in intracellular
volume fraction can contribute to … The amiloride-sensitive epithelial Na + channel (ENaC) and …
volume fraction can contribute to … The amiloride-sensitive epithelial Na + channel (ENaC) and …
… and Glyceraldehyde-3-Phosphate Dehydrogenase-Dependent Regulation of Epithelial Sodium Channels in hPheo1 Wild-type and SDHB Knockdown Cells
… in glioma cells (10); contribute to increased proliferation and … cancer cell behavior have
focused on changes in cell volume. … to contribute to amiloride-sensitive current in cancer cells (39)…
focused on changes in cell volume. … to contribute to amiloride-sensitive current in cancer cells (39)…
[HTML][HTML] Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3
Y Tian, P Bresenitz, A Reska, L El Moussaoui… - Scientific reports, 2017 - nature.com
… contribution of ASIC3 to ASIC currents in most R54 cells. In … and R8 cells have a similar
amiloride-sensitive basal current, … HGF/SF and menthol increase human glioblastoma cell …
amiloride-sensitive basal current, … HGF/SF and menthol increase human glioblastoma cell …