… Amiodarone is a popular antiarrhythmic agent but potential … (diltiazem and verapamil),
β-blockers and digoxin, etc. … , digoxin (we should discontinue or divide the dose of digoxin and …

… of quinidine and verapamil on arrythmia burden over 3 years … Amiodarone's effect on
repolarization can be additive to the … long QT without quinidine), administration of digoxin, and …

… % however digoxin is not effective in those with increased sympathetic drive. Amiodarone is
… restricted to the management of short QT syndromes and Brugada syndrome (ie quinidine). …

… Positive inotropic drugs such as digitalis, that inhibits the Na+… 1 antiarrhythmic effects of
quinidine on INaL 10 µM quinidine … is the main metabolite of amiodarone has beneficial effect by …

… [1,2] Digoxin is the only available preparation of digitalis in the United States. Cardiac … who
have conditions which may alter their sensitivity to digoxin. Quinidine, verapamil, amiodarone, …

… digoxin, this result in decrease anticoagulant activity of warfarin and plasma level of digoxin
as it is … digitalis toxicity and can antagonize the antiarrhythmic activity of quinidine, lidocaine, …

… was created when it was discovered that both quinidine and … like d-sotalol and amiodarone.
These authors however, … pharmacological actions, including digitalis, adenosine, ivabradine, …

… require monitoring closely to avoid digitalis toxicity. Amiodarone, verapamil, quinidine, and
diltiazem increase the serum levels of digoxin and can lead to toxicity. The recommendation …

… with P-gp inhibitors (verapamil, amiodarone, carvedilol, quinidine, … This is important to
remember because amiodarone has a … Co-administration of digoxin (P-gp substrate) increased the …