… Quinidine, ambasilide and diltiazem inhibit I to,fast in the open … of Ca 2 + overload may be
accelerated by digitalis toxicity, β-… Moreover, the Class IV antiarrhythmic drug, verapamil, has …

… while basic drugs, eg morphine, quinine, etc. are largely ionized and are absorbed only on …
of oral contraceptives and digoxin. Drugs can also alter absorption by gut wall effects: altering …

… Interestingly, grapefruit juice did not affect the metabolism of quinine by liver CYP3A4, thus …
for 14 days did not affect digoxin pharmacokinetics and thus is unlikely to affect P-gp function […

… concentrations in patients whose dose was not changed for ten or more days. However,
the results of the study were not enough for the support of using saliva for digoxin’s TDM to …

… , atorvastatin, verapamil, felodipine, and amiodarone, leading … Other drugs, such as quinidine,
may be substrates for both … binding (eg propranolol, amiodarone, nifedipine, and digoxin). …

… quinidine, amiodarone, and verapamil (increased concentration) with dabigatran [38,50].
Dabigatran and p-gp inhibitors should not … digoxin, atorvastatin, and esomeprazole did not alter …

… may include an increase in the frequency or severity of the side effects but generally would
not require a … B inducing hypokalaemia may cause arrhythmia and potentiate digitalis toxicity. …

… tumors to chemotherapeutic drugs without toxic effects to date. The MDR inhibitors that were
initially recognized, such as verapamil and cyclosporine A, are actually substrates for ABC …

… , verapamil, erythromycin, quinidine, and amiodarone). Citation9 There … digoxin (9.5%) or
atorvastatin (1.7%). Citation14 Concomitant administration of digoxin and edoxaban does not …

… Additive hypotensive effect with nitrates and antihypertensive drugs; additive bradycardia
with digoxin; decreases effects of dopamine and dobutamine; unopposed α-adrenergic …