… Orally administered quinidine increased the peak and total exposure to … Amiodarone has a
long half-life of 58 days (range 15–142 … Digoxin (P-gp substrate): coadministration of digoxin …

… , quinidine and verapamil [33]. While, the second (valspodar) [30] and third generation (tariquidar
[34], zosuquidar) [31] of ABCs blocker were specifically design to reverse MDR with no …

… Amiodarone vs quinidine + verapamil for persistent AF … Amiodarone vs quinidine in the
prophylaxis of AF after DCC … Amiodarone can also increase digoxin levels, therefore dose …

… , OCTN1 is inhibited by quinidine, levofloxacin and verapamil (… compounds may alter the
elimination of digoxin, quinidine, … On the other hand, P-gp is induced by many drugs, including …

… Interestingly, grapefruit juice did not affect the metabolism of quinine by liver CYP3A4, thus …
for 14 days did not affect digoxin pharmacokinetics and thus is unlikely to affect P-gp function […

… of coadministration with digoxin (0.25 mg once daily), it was demonstrated that apixaban …
is required when coadministered with verapamil but not with amiodarone or quinidine. In the …

… Quinidine, ambasilide and diltiazem inhibit I to,fast in the open … of Ca 2 + overload may be
accelerated by digitalis toxicity, β-… Moreover, the Class IV antiarrhythmic drug, verapamil, has …

… drugs, including digoxin and adenosine, do not fit primarily … Quinidine is associated with a
number of contraindications … iodine that is associated with some side effects of amiodarone, …

… % however digoxin is not effective in those with increased sympathetic drive. Amiodarone is
… restricted to the management of short QT syndromes and Brugada syndrome (ie quinidine). …

… , atorvastatin, verapamil, felodipine, and amiodarone, leading … Other drugs, such as quinidine,
may be substrates for both … binding (eg propranolol, amiodarone, nifedipine, and digoxin). …