Effects of antihypertensive agents on intestinal contractility in the spontaneously hypertensive rat: angiotensin receptor system downregulation by losartan
GS Patten, MY Abeywardena - Journal of Pharmacology and Experimental …, 2017 - ASPET
… the ileum and colon were induced to contract ex vivo by KCl; … carbachol, angiotensin II,
and prostaglandin E 2 (PGE 2 ). … muscles and contraction of longitudinal muscle in the small …
and prostaglandin E 2 (PGE 2 ). … muscles and contraction of longitudinal muscle in the small …
[PDF][PDF] Angiotensin II receptor blockers modulate intestinal motility of aged rats
AM Abood - Ain Shams Medical Journal, 2019 - researchgate.net
… The rats used in this study underwent an ex-vivo and in-vitro … lower average duration of
contraction in the old rats, when … of AT1 receptors located on smooth muscle cells in different GI …
contraction in the old rats, when … of AT1 receptors located on smooth muscle cells in different GI …
Histomorphometry changes and decreased reactivity to angiotensin II in the ileum and colon of streptozotocin-induced diabetic rats
M Esteves-Monteiro, D Menezes-Pinto… - International Journal of …, 2022 - mdpi.com
… , AngII-induced smooth muscle contraction was lower in diabetic rats, except in the distal
colon. … Contrary to what happens when we look at the intestinal wall as a whole, the differences …
colon. … Contrary to what happens when we look at the intestinal wall as a whole, the differences …
Angiotensin II type II receptors and colonic dysmotility in 2, 4‐dinitrofluorobenzenesulfonic acid‐induced colitis in rats
MG Zizzo, M Auteri, A Amato, G Caldara… - …, 2017 - Wiley Online Library
… rats were characterized in vitro. Transcripts encoding for Ang … , low-frequency contractions,
which resulted significantly lower … II induces contractile effects in the longitudinal muscle of rat …
which resulted significantly lower … II induces contractile effects in the longitudinal muscle of rat …
Aging modifies receptor expression but not muscular contractile response to angiotensin II in rat jejunum
… , in vitro, the contractile responses induced by Ang II, in … rat anococcygeus smooth muscle
and in inflamed colon [8, 29]. … jejunum, the Ang II–induced contraction was partially reduced by …
and in inflamed colon [8, 29]. … jejunum, the Ang II–induced contraction was partially reduced by …
Effect of angiotensin II-induced arterial hypertension on the voltage-dependent contractions of mouse arteries
P Fransen, CE Van Hove, AJA Leloup… - … -European Journal of …, 2016 - Springer
… muscle cells. The EC 50 for extracellular K + obtained in … current induced contraction curves
of conduit vessels of mice … -type Ca 2+ channels, we plotted individual data for in vivo arterial …
of conduit vessels of mice … -type Ca 2+ channels, we plotted individual data for in vivo arterial …
[PDF][PDF] Colonic reactivity to Angiotensin II in an experimental model of inflammatory bowel disease
MF Duarte - 2018 - repositorio-aberto.up.pt
… Angiotensin II (Ang II) regulates the smooth muscle tone of … to Ang II in the colon of
TNBS-induced rats, particularly in the … IBD, which cannot be simulated using in silico or in vitro …
TNBS-induced rats, particularly in the … IBD, which cannot be simulated using in silico or in vitro …
Interaction between the renin–angiotensin system and enteric neurotransmission contributes to colonic dysmotility in the TNBS-induced model of colitis
M Ferreira-Duarte, T Rodrigues-Pinto, T Sousa… - International Journal of …, 2021 - mdpi.com
… Angiotensin II (Ang II) regulates colon contraction, acting not only directly on smooth muscle
… in subsequent in vitro functional experiments (see below): two segments from the proximal …
… in subsequent in vitro functional experiments (see below): two segments from the proximal …
The renin–angiotensin system in gastrointestinal functions
MG Zizzo, R Serio - Angiotensin, 2023 - Elsevier
… The few in vitro studies of angiotensin II effects on gastric tissue indicated its ability to …
smooth muscle preparations. Indeed, angiotensin II-induced contractions in human small intestine …
smooth muscle preparations. Indeed, angiotensin II-induced contractions in human small intestine …
… , angiotensin II type II receptor antagonist, inhibits oxidative stress and inflammation in 2, 4-dinitrobenzene sulfonic acid-induced colitis in rat and ameliorates colonic …
… the impairment of the muscle contractility in vitro in the course … amplitude of the spontaneous
colonic contractions, as well as … , in vivo treatment with PD123319 matched the in vitro effects…
colonic contractions, as well as … , in vivo treatment with PD123319 matched the in vitro effects…