Clinical implications of identifying pathogenic variants in individuals with thoracic aortic dissection

BN Wolford, WE Hornsby, D Guo, W Zhou… - Circulation: Genomic …, 2019 - Am Heart Assoc
aortic dissection (n=235) or rupture (n=5) and 258 controls matched for age, sex, and
ancestry. Blinded to case-control status, we annotated variants in 11 genes for pathogenicity. …

Traditional Cardiovascular Risk factors and their relation to future surgery for Valvular Heart Disease or Ascending Aortic Disease: a case–referent study

J Ljungberg, B Johansson, KG Engström… - Journal of the …, 2017 - Am Heart Assoc
… of the ascending aorta performed within 3 large, populationbasedangiotensinconverting
enzyme inhibitor; AR, aortic … for ascending aortic disease, 34% had an acute dissection. The …

Antihypertensive drug class in combination with lipid lowering treatment for primary prevention of cardiovascular disease in the elderly

…, Second Australian National Blood Pressure Study … - Heart & Lung, 2022 - Elsevier
… for two-thirds of the population-based modifiable risk of … blocker (ARB) or an
angiotensin-converting-enzyme inhibitor (ACE-I) … A large nested case-control study 21 suggests …

Sex differences in risk factors for aneurysmal subarachnoid haemorrhage: systematic review and meta-analysis

S Rehman, BW Sahle, RV Chandra, M Dwyer… - Journal of the …, 2019 - Elsevier
… SAH results from the rupture of an aneurysm in approximately … consequently increasing the
risk of rupture. The risk factors for … 19 studies (case-control studies = 15, cohort studies = 4) as …

[HTML][HTML] Systematic review and Meta-Analysis of Mendelian randomisation analyses of Abdominal aortic aneurysms

M Ibrahim, S Thanigaimani, TP Singh, D Morris… - IJC Heart & …, 2021 - Elsevier
… Abdominal aortic aneurysm (AAA) rupture is responsible for approximately … -blockers,
angiotensin converting enzyme inhibitors, angiotensin receptor blockers and mast cell inhibitors, …

[HTML][HTML] Exploring drug re-purposing for treatment of abdominal aortic aneurysms: a systematic review and meta-analysis

JSS Kristensen, L Krasniqi, LM Obel… - European Journal of …, 2023 - Elsevier
… , randomised population based screening studies, which had … .20, 21, 22 The studies in
question had collected all the … year nested case control study of Danish ruptured AAA cases…

Pharmacologic management of aneurysms

JH Lindeman, JS Matsumura - Circulation research, 2019 - Am Heart Assoc
… to as a model of aortic dissection. Hence, conclusions based on … The ACE (angiotensin-converting
enzyme) inhibitors are the … studies, 74,75 and a population-based case-control study

Repurposing of approved cardiovascular drugs

J Ishida, M Konishi, N Ebner, J Springer - Journal of translational medicine, 2016 - Springer
… , beta-blockers, angiotensin converting enzyme inhibitors, angiotensin II receptor blockers, …
In clinical fields, a casecontrol study first demonstrated that aspirin use was associated …

Epidemiology of thoracoabdominal aortic aneurysms

JB Stoecker, GJ Wang - Seminars in vascular surgery, 2021 - Elsevier
… , whereas population-based studies include all ruptures, even … blocker, statin,
angiotensin-converting enzyme inhibitor [ACEi] … of β-blockers in TAAAs secondary to aortic

[PDF][PDF] The aging population and research into treatments for abdominal aortic aneurysms

R Umebayashi, HA Uchida, J Wada - Acta Medica Okayama, 2019 - scholar.archive.org
… Hackam DG, Thiruchelvam D and Redelmeier DA: Angiotensinconverting enzyme
inhibitors and aortic rupture: a population-based case-control study. Lancet (2006) 368: 659-665. …