Elastase‐2, an angiotensin II‐generating enzyme, contributes to increased angiotensin II in resistance arteries of mice with myocardial infarction
… family member 2A, alternatively generates Ang II in rat arteries. Myocardial … II‐generation
in resistance arteries are unknown. We hypothesized that ELA‐2 contributes to vascular Ang II …
in resistance arteries are unknown. We hypothesized that ELA‐2 contributes to vascular Ang II …
Angiotensin converting enzyme 2: a double-edged sword
… Cleavage of angiotensin I by ACE generates angiotensin II, … -2 through its ability to (1)
sequester viral particles to prevent their … ACE2 and (2) limit activities of angiotensin II and increase …
sequester viral particles to prevent their … ACE2 and (2) limit activities of angiotensin II and increase …
A new perspective on the renin-angiotensin system
A Martyniak, PJ Tomasik - Diagnostics, 2022 - mdpi.com
… It is also known as angiotensinase and consists of 340 … in the blood vessel wall, responding
to changes in blood flow … (1) degradation of angiotensin I and angiotensin II to limit substrate …
to changes in blood flow … (1) degradation of angiotensin I and angiotensin II to limit substrate …
The angiotensin-(1-7) axis: formation and metabolism pathways
MC Chappell - Angiotensin-(1-7) A Comprehensive Review, 2019 - Springer
… Neprilysin is located on the vascular surface of blood vessels … The higher JMV dose may
block other peptidases including … angiotensinase that hydrolyzed the Asp 1 -Arg 2 bond to Ang …
block other peptidases including … angiotensinase that hydrolyzed the Asp 1 -Arg 2 bond to Ang …
[HTML][HTML] Local angiotensin II promotes adipogenic differentiation of human adipose tissue mesenchymal stem cells through type 2 angiotensin receptor
VY Sysoeva, LV Ageeva, PA Tyurin-Kuzmin… - Stem Cell Research, 2017 - Elsevier
… As a net result Ang II causes blood vessel wall contraction … -well plate at low density to prevent
cell-to-cell communications … and Ang 1–7, including renin (REN), ACE and angiotensinase …
cell-to-cell communications … and Ang 1–7, including renin (REN), ACE and angiotensinase …
ACE2 in the renin–angiotensin system
T Verano-Braga, ALV Martins, D Motta-Santos… - Clinical …, 2020 - portlandpress.com
… mainly by the octapeptide angiotensin II (Ang II) and its … an alternative pathway to generate
the octapeptide Ang II [2]. … restricted to the RAS [3,9]; however, its action converting Ang …
the octapeptide Ang II [2]. … restricted to the RAS [3,9]; however, its action converting Ang …
Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?
MC Chappell - American Journal of Physiology-Heart and …, 2016 - journals.physiology.org
… angiotensin-converting enzyme (ACE) to form angiotensin II (… an inhibitor cocktail to prevent
nonspecific hydrolysis by … other ANG II-generating enzymes (cathepsin G, elastase-2) and …
nonspecific hydrolysis by … other ANG II-generating enzymes (cathepsin G, elastase-2) and …
Deficiency of the angiotensinase aminopeptidase A increases susceptibility to glomerular injury
… glomerular podocytes and tubular epithelia and metabolizes angiotensin II (AngII), a
peptide … The horizontal dashed line in the bar graph denotes the lower limit of detection. *P<0.001. …
peptide … The horizontal dashed line in the bar graph denotes the lower limit of detection. *P<0.001. …
Angiotensins and their receptors in cardiac and vascular injury
S Schmull, Z Wang, L Gao, J Lv, J Li… - Current Hypertension …, 2016 - ingentaconnect.com
… is considered as the main mediator of this system but angiotensin IIderived peptides were
also shown … Angiotensinases restrict locally generated angiotensin II to the blood vessel wall. …
also shown … Angiotensinases restrict locally generated angiotensin II to the blood vessel wall. …
Prolylcarboxypeptidase Alleviates Hypertensive Cardiac Remodeling by Regulating Myocardial Tissue Angiotensin II
BY Nguyen, F Zhou, P Binder, W Liu… - Journal of the …, 2023 - Am Heart Assoc
… could prevent many cardiac diseases such as angiotensin II–… wall was also significantly
increased in angiotensin II–… that can metabolize angiotensin II to generate angiotensin 1‐7 in …
increased in angiotensin II–… that can metabolize angiotensin II to generate angiotensin 1‐7 in …