Anti-angiogenic isoform of vascular endothelial growth factor-A in cardiovascular and renal disease
R Kikuchi, M Stevens, K Harada, S Oltean… - Advances in clinical …, 2019 - Elsevier
Accumulating evidence suggests that pathologic interactions between the heart and the
kidney can contribute to the progressive dysfunction of both organs. Recently, there has
been an increase in the prevalence of cardiovascular disease (CVD) and chronic kidney
disease (CKD) due to increasing obesity rates. It has been reported that obesity causes
various heart and renal disorders and appears to accelerate their progression. Vascular
endothelial growth factor-A (VEGF-A) is a major regulator of angiogenesis and vessel …
kidney can contribute to the progressive dysfunction of both organs. Recently, there has
been an increase in the prevalence of cardiovascular disease (CVD) and chronic kidney
disease (CKD) due to increasing obesity rates. It has been reported that obesity causes
various heart and renal disorders and appears to accelerate their progression. Vascular
endothelial growth factor-A (VEGF-A) is a major regulator of angiogenesis and vessel …
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