… In the recent years, we have observed an increase in the of discovery and development of
natural anti-cancer drugs not only for their efficacy and lower side effect, but also for low cost. …

… Anti-cancer effects of naturally occurring compounds through modulation of signal
transduction and miRNA expression in human colon cancer …

… into non-chemoresistant CRC cells by modulating … , tumor cells often develop resistance to
anti-cancer agents … signal transducer and activator of transcription’ (STAT)-3 signaling in CRC …

… signal transduction pathways related to its anti-cancer effects. … apoptosis of HCT116 human
colon cancer cells via a caspase-… -tumor activity, namely regulation of EMT via modulation of …

… /janus kinase-2/signal transducer and activator of transcription … induced apoptosis in human
HCT116 colon cancer cells, thus … to cause regression of (CIN) via modulation of the IL-6 level …

… cells (NF-ĸB) pathway, mitogen-activated protein kinases (MAPKs), proteasome pathway,
insulin-like growth factor-I mediated signal transduction … kinase–signal transducer and activator …

… Signal transducer and activator of transcription 3 (STAT3) is … decreased migration and
invasion via modulation of STAT3. … in breast cancer, colorectal cancer, lung cancer, sarcoma …

… active compounds elicit chemopreventive potency through … of naturally occurring plant
fibers as related to miRNA and … cancers, including colorectal cancer, via modulating miRNAs (…

… ’s mechanism as an anti-cancer compound, offering a novel … al. found that ATL-1
significantly inhibits the signal transducer … proteins originating from colorectal cancer cells, thus …

… an anticancer effect on the human colon cancer cell line HT-… , and angiogenesis through
inhibiting the signal transducer and … is involved in inducing apoptosis through modulation of the …