Seeking new anti-cancer agents from autophagy-regulating natural products

F Hua, S Shang, ZW Hu - Journal of Asian natural products …, 2017 - Taylor & Francis
… products through modulation of autophagy activity. … Signal transducer and activator of
transcription 3 (STAT3) is an … leukemia, human colon cancer and a variety of solid tumor systems. …

[HTML][HTML] Garcinol exhibits anti-neoplastic effects by targeting diverse oncogenic factors in tumor cells

V Aggarwal, HS Tuli, J Kaur, D Aggarwal, G Parashar… - Biomedicines, 2020 - mdpi.com
… )/β-catenin, signal transducer and activator of transcription 3 (… In human colon cancer cells
(HT-29), garcinol treatment was … compound, mediates its anti-cancer effects via modulation of …

[HTML][HTML] Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects

SM Tang, XT Deng, J Zhou, QP Li, XX Ge… - Biomedicine & …, 2020 - Elsevier
… -small cell lung cancer, colon cancer, glioma and many other … As a natural product, quercetin
is a flavonoid compound, and … can directly regulate the expression of miRNA and the level …

[HTML][HTML] Steroidal saponins: Naturally occurring compounds as inhibitors of the hallmarks of cancer

S Bouabdallah, A Al-Maktoum, A Amin - Cancers, 2023 - mdpi.com
anti-cancer agents. Steroidal saponins are a group of … against STAT3 in the colon cancer
cell line SW480 according to … in intracellular iron levels via the modulation of transferrin and …

[HTML][HTML] Bioactive Compounds of Dietary Origin and Their Influence on Colorectal Cancer as Chemoprevention

P Delgado-Gonzalez, EN Garza-Treviño… - Life, 2023 - mdpi.com
… types of cancer, including colorectal cancer, by modulating various … are involved in pro- or
anti-cancer actions [57]. Several … -tumor effect by regulating the signal transduction pathways …

[HTML][HTML] Chemoprevention of colorectal cancer by dietary compounds

T Costea, A Hudiță, OA Ciolac, B Gălățeanu… - International journal of …, 2018 - mdpi.com
… , regulation of cellular signal transduction pathways and … anti-cancer potential of β-carotene
was attributed to cell cycle arrest and apoptosis induction by modulating the expression

Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator

Z Jahanafrooz, N Motamed, B Rinner, A Mokhtarzadeh… - Life sciences, 2018 - Elsevier
… of silibinin to trigger signal transduction pathways involved in … for anti-cancer efficacy in a
variety of cancers models and it … Human colon cancer SW480 and SW620 (metastatic) cells

[HTML][HTML] The influence of diet on anti-cancer immune responsiveness

L Soldati, L Di Renzo, E Jirillo, PA Ascierto… - Journal of translational …, 2018 - Springer
… be modulated by the nutritional status and secondarily affect … (MUFA) and phenolic compound,
including simple phenols, … of colorectal cancer [79], breast cancer treatment efficacy [80]…

[HTML][HTML] Pharmacological effects of cisplatin combination with natural products in cancer chemotherapy

S Dasari, S Njiki, A Mbemi, CG Yedjou… - International journal of …, 2022 - mdpi.com
… action by triggering apoptosis through modulation of mitogen-… treatment option for adjuvant
therapy of colon carcinoma [12]. … demonstrated that the anti-cancer effects of curcumin alone …

[HTML][HTML] Signaling pathways in cancer metabolism: mechanisms and therapeutic targets

M You, Z Xie, N Zhang, Y Zhang, D Xiao, S Liu… - Signal Transduction …, 2023 - nature.com
… demands of cancer cells and governs their behaviors by modulating the types and … cancer
treatment. For example, the drugs for bone metastasis and colon cancer, which are microRNA