Anti-inflammatory therapies for cardiovascular disease: signaling pathways and mechanisms
S Martínez-Hervás, H González-Navarro - Revista Española de Cardiología …, 2019 - Elsevier
Cardiovascular diseases (CVD) are the clinical manifestation of atherosclerosis, a chronic
inflammatory disease promoted by several risk factors such as dyslipidemia, type 2 diabetes
mellitus, hypertension, and smoking. Acute CVD events are the result of an unresolved
inflammatory chronic state that promotes the rupture of unstable plaque lesions. Of note, the
existing intensive therapies modify risk factors but do not prevent life-threatening recurrent
ischemic events in high-risk patients, who have a residual inflammatory risk displayed by …
inflammatory disease promoted by several risk factors such as dyslipidemia, type 2 diabetes
mellitus, hypertension, and smoking. Acute CVD events are the result of an unresolved
inflammatory chronic state that promotes the rupture of unstable plaque lesions. Of note, the
existing intensive therapies modify risk factors but do not prevent life-threatening recurrent
ischemic events in high-risk patients, who have a residual inflammatory risk displayed by …
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