Anti-nociceptive mechanisms of flavonoids-rich methanolic extract from Terminalia coriacea (Roxb.) Wight & Arn. leaves

MSA Khan, N Ahmed, M Arifuddin, ZA Zakaria… - Food and chemical …, 2018 - Elsevier
In view of the report on anti-nociceptive activity of Leathery Murdah, Terminalia coriacea
{Roxb.} Wight & Arn.(Combretaceae) leaves, the present study was conducted to isolate the
active constituents and identify the underlying mechanisms. The methanolic extract of T.
coriacea leaves (TCLME) at doses 125, 250 and 500 mg/kg orally, was subjected to various
in-vivo assays in acetic acid induced writhing and formalin induced paw-licking tests with
aspirin (100 mg/kg) and morphine (5 mg/kg) as reference drugs. Three flavonoids, rutin …

Anti-nociceptive mechanisms of flavonoids-rich methanolic extract from Terminalia coriacea (Roxb.) Wight & Arn. leaves.

AK Mohammed Safwan, NA Nishat Ahmed, M Misbah… - 2018 - cabidigitallibrary.org
In view of the report on anti-nociceptive activity of Leathery Murdah, Terminalia coriacea
{Roxb.} Wight & Arn.(Combretaceae) leaves, the present study was conducted to isolate the
active constituents and identify the underlying mechanisms. The methanolic extract of T.
coriacea leaves (TCLME) at doses 125, 250 and 500 mg/kg orally, was subjected to various
in-vivo assays in acetic acid induced writhing and formalin induced paw-licking tests with
aspirin (100 mg/kg) and morphine (5 mg/kg) as reference drugs. Three flavonoids, rutin …
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