… , activated proteases release heparin-binding epidermal growth factors (HB-EGF) and
amphiregulin, which have antimicrobial activity and are responsible for stimulating the expression …

… DispersinB has also shown efficacy in some in vivo models (… agents do not have antimicrobial
activity themselves, but are … include wound topical agents and antibacterial therapies for …

… peptide KSL-W. When formulated as a wound gel, the combination peptide-dispersin B …
contribute in translating peptide-based combinations into multifunctional antibiofilm drugs. …

… Dispersin B combined with broad spectrum antimicrobial peptide KSL-W as a wound gel …
could have anti-biofilm activity and could increase antibiotic efficacy against biofilms (Fig. 9) […

… wound healing. Further developments in prospective strategies for topical anti-biofilm therapy
for infected wounds … modalities, based on intrinsic antimicrobial activity, light-induced ROS …

… the feasibility of AMPs as anti-biofilm agents. Finally, we … wound healing, including their
direct antimicrobial effect which prevents infection that would otherwise delay wound healing…

… Antibiofilm and antimicrobial efficacy of dispersin B®-KSL-W peptide-based wound gel against
chronic wound … gene expression modulation by antimicrobial decapeptide KSL-W, BMC …

… that KSL-W is also effective towards other bacteria associated with wound healing [46]. …
sequence of KSL-W is necessary for its full antibacterial activity. Moreover, each amino acid of …

… wound gel combining DispersinB ® , an antibiofilm enzyme, with Pluronic F-127, a gelling
agent, and KSL-W… in vitro antibiofilm and antimicrobial activity against chronic wound infection …

… , their mode of action, and anti-biofilm activity both alone and in … possess microbe specific
antimicrobial activity li e inhibition … However, peptide-based treatment of biofilm infections is li …