Current state and challenges in developing oral vaccines
… Oral immunization has the potential to improve vaccine … These antibody-secreting lymphocytes
are critical in the … tend to be less immunogenic than their whole-cell counterparts. Current …
are critical in the … tend to be less immunogenic than their whole-cell counterparts. Current …
Oral immunization with Shigella sonnei WRSs2 and WRSs3 vaccine strains elicits systemic and mucosal antibodies with functional anti-microbial activity
S Shrivastava, AB Agnememel, E Ndungo, D Islam… - Msphere, 2024 - Am Soc Microbiol
… assessed the safety and immunogenicity of the live attenuated S. … and ALS, antibody secreting
cells, and stool IgA (33, 37). … proteomic analysis of human enteroids (primary epithelial cell …
cells, and stool IgA (33, 37). … proteomic analysis of human enteroids (primary epithelial cell …
Sublingual immunization with the phosphate‐binding‐protein (PstS) reduces oral colonization by Streptococcus mutans
EL Ferreira, MT Batista… - Molecular Oral …, 2016 - Wiley Online Library
… were collected to detect antibody-secreting cells or cytokines … evaluated the antigenic and
immunogenic properties of the S. mutans protein, PstS, to determine its feasibility as a vaccine …
immunogenic properties of the S. mutans protein, PstS, to determine its feasibility as a vaccine …
Delivery of antigen to nasal-associated lymphoid tissue microfold cells through secretory IgA targeting local dendritic cells confers protective immunity
N Rochereau, V Pavot, B Verrier, F Jospin… - Journal of Allergy and …, 2016 - Elsevier
… poor antigen stability, altered immunogenicity, and safety … after nasal immunization, p24-SIgA
is quickly taken up by M cells … ELISpot assays for IgG and IgA antibody-secreting cells were …
is quickly taken up by M cells … ELISpot assays for IgG and IgA antibody-secreting cells were …
Cross-reactivity and avidity of antibody responses induced in humans by the oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine ETVAX
S Leach, A Lundgren, N Carlin, M Löfstrand… - Vaccine, 2017 - Elsevier
… /I-positive ETEC bacteria mounted antibody secreting cell responses to the homologous CF
… and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing …
… and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing …
Composition of gut microbiota and its influence on the immunogenicity of oral rotavirus vaccines
CA Magwira, MB Taylor - Vaccine, 2018 - Elsevier
… In this review article, we discuss the concept that the disparity in the efficacy of … They also
had a higher numbers of IgM antibody secreting cells (p = 0.02) than those only given the …
had a higher numbers of IgM antibody secreting cells (p = 0.02) than those only given the …
Construction of an oral vaccine for transmissible gastroenteritis virus based on the TGEV N gene expressed in an attenuated Salmonella typhimurium vector
D Zhang, X Huang, X Zhang, S Cao, X Wen… - Journal of virological …, 2016 - Elsevier
… Based on the analysis of cytokines induced by the oral vaccine SL7207 (pVAX-N) in this …
cellular immunity against TGEV infection, proving the effectiveness of the developed vaccine. …
cellular immunity against TGEV infection, proving the effectiveness of the developed vaccine. …
… 1 randomized, placebo-controlled, observer-blinded trial to evaluate the safety and immunogenicity of inactivated Streptococcus pneumoniae whole-cell vaccine in …
CA Keech, R Morrison, P Anderson… - The Pediatric …, 2020 - journals.lww.com
… (eg, high yields, low costs, etc.), if such a vaccine can be shown to induce a strong … to
evaluate the safety, tolerability and immunogenicity of an experimental SPn whole cell vaccine …
evaluate the safety, tolerability and immunogenicity of an experimental SPn whole cell vaccine …
Evaluation of the oral immunogenicity of M cell-targeted tetravalent EDIII antigen for development of plant-based edible vaccine against dengue infection
BY Kim, MY Kim - Plant Cell, Tissue and Organ Culture (PCTOC), 2019 - Springer
… vaccine development. In this study, we evaluated an ‘all-in-one’ tetravalent dengue vaccine
… ELISPOT, showing the mean number of antibody-secreting cells from triplicate cultures; WT …
… ELISPOT, showing the mean number of antibody-secreting cells from triplicate cultures; WT …
[图书][B] Evaluation of Human T and B Cell Immune Responses to Enteric Vaccines in Human Nasopharynx-Associated Lymphoid Tissues
MA Leon-Rios - 2022 - search.proquest.com
… was shown after a three-dose oral immunization with α-GalCer-… or effector antibody-secreting
plasma cells, respectively (37-… focus on the evaluation of immunogenicity of enteric vaccines…
plasma cells, respectively (37-… focus on the evaluation of immunogenicity of enteric vaccines…