… understanding of Tregs and other regulatory subsets has led to the possibility that transplant
… /6 (H2 b ) transplant model and was associated with T cell mediated immune regulation …

… or thymocytes, could transfer antigen-specific transplant tolerance or delay rejection. Our …
IJ and the failure to clone an antigen-specific suppressor T cell. Suppressor T cells were …

… The best characterized subset of … antigen-specific TCR suppressed antigen-stimulated
T cell responses. However, they were less efficient than Tregs expressing a viral antigen-specific …

… Under our culture conditions using CsA to suppress T cell … as effective stimulators of
antigen-specific regulatory T cells. … and expand in culture potent antigen-specific Tregs that can …

… candidate to induce transplantation tolerance in human. … T cell death and donor specific
transplantation tolerance … /– CD4 + and CD8 + T cell subsets among PBMCs at day 10. CD45RC-…

… Treg-mediated immune tolerance in vivo. These treatments can increase the expansion
and/or function of polyclonal or antigen-specific Treg subsets depending on the underlying …

… Regulatory T cells (Tregs) are a suppressive subset of T cells … foreign antigen-specific Tregs
is the maintenance of tolerance … , which is focused on developing regulatory T-cell therapies. …

… + effector T cell subsets is best … regulatory T cell immune-modulatory therapy in patients
with autoimmune diseases. Autoimmune patients undergo apheresis, out of which regulatory T …

… tetramers to identify endogenous antigen-specific T cells, and … specifically recognize a
CD4 + T cell subset comprising ~7.5% … T cell (Tconv) but do not promote regulatory T cell (Treg) …

… The concept of regulatory T cell (T reg ) therapy in transplantation is now a reality. … induction
of tolerance. However, in this study the iT regs were deemed to be donor-antigen specific, …