Bovine lactoferrin-derived ACE inhibitory tripeptide LRP also shows antioxidative and anti-inflammatory activities in endothelial cells

Y Gu, J Wu - Journal of Functional Foods, 2016 - Elsevier
identify potent ACE inhibitory peptides from bovine lactoferrin hydrolysate prepared by
thermolysin, pepsin … application of bovine lactoferrin as a source of antihypertensive peptides was …

Identification of dual-function bovine lactoferrin peptides released using simulated gastrointestinal digestion

M Tu, S Xu, Z Xu, S Cheng, D Wu, H Liu, M Du - Food Bioscience, 2021 - Elsevier
… The LF hydrolysate produced using pepsin digestion showed antihypertensive (Ruiz-Giménez …
Therefore, the LFH may be able to exert an antihypertensive effect by inhibiting the ACE …

Vasoactive properties of antihypertensive lactoferrin-derived peptides in resistance vessels: Effects in small mesenteric arteries from SHR rats

A García-Tejedor, P Manzanares, M Castelló-Ruiz… - Life sciences, 2017 - Elsevier
Bovine lactoferrin (LF) hydrolysates and peptides identified thereof have … effects and
mechanisms of an ultrafiltered (< 3 kDa) pepsin LF hydrolysate (LFH) and a heptapeptide identified

Molecular binding mechanism and identification of novel anti-hypertensive and anti-inflammatory bioactive peptides from camel milk protein hydrolysates

P Mudgil, B Baby, YY Ngoh, H Kamal, R Vijayan… - Lwt, 2019 - Elsevier
… slightly light bands of lactoferrin and serum albumin were also detected. Following enzymatic
… Digestion of bovine α-S 2 and κ-casein with pepsin released ACE inhibitory peptides with …

Structure and Function Study of Food Protein-Derived ACE Inhibitory Peptides

Y Gu - 2016 - era.library.ualberta.ca
hypertension. The objectives of this thesis were to 1) … CHAPTER 5-Bovine lactoferrin derived
ACE inhibitory tripeptide … protein hydrolysates digested by thermolysin, pepsin and trypsin …

Recent research in antihypertensive activity of food protein-derived hydrolyzates and peptides

ASM Saleh, Q Zhang, Q Shen - Critical reviews in food science and …, 2016 - Taylor & Francis
… and the antihypertensive properties of casein-hydrolyzed … and characterization of a novel
antihypertensive angiotensin I-… The maximum antihypertensive effect for the pepsin digest (–…

Bioactive Peptides and Their Presence in Some Milk Species

B Palabıçak, M Akın, M Akın, A Çelikel - Harran Üniversitesi Mühendislik … - dergipark.org.tr
… of milk in the gastrointestinal tract or hydrolysis by proteolytic enzymes (pepsin, trypsin and …
antihypertensive and antioxidative effects. Most studies have used cow milk protein to identify

Novel ACE inhibitory peptides derived from whey protein hydrolysates: Identification and molecular docking analysis

X Li, C Feng, H Hong, Y Zhang, Z Luo, Q Wang, Y Luo… - Food Bioscience, 2022 - Elsevier
hydrolysate could be a suitable resource for obtaining novelnovel ACE inhibitors for
hypertension management. … For those peptides that cannot be hydrolyzed by pepsin, trypsin, and …

Lactoferrin Isolation and Hydrolysis from Red Deer (Cervus elaphus) Milk and the Antibacterial Activity of Deer Lactoferrin and Its Hydrolysates

Y Wang, AEDA Bekhit, SL Mason, JD Morton - Foods, 2020 - mdpi.com
Cow lactoferrin (Lf) has 708 amino acids with molecular … A great number of antimicrobial
peptides have been identified within … Both deer and cow Lf were susceptible to pepsin and were …

Isolation and characterization of lactoferrin peptides with stimulatory effect on osteoblast proliferation

F Fan, M Tu, M Liu, P Shi, Y Wang… - Journal of agricultural …, 2017 - ACS Publications
… to isolate and identify peptides with stimulatory effect on osteoblast … Bovine lactoferrin (95.41%
purity) used in this study was … In the present study, lactoferrin was hydrolyzed by pepsin to …