The pleiotropic functions of reactive oxygen species in cancer
K Wu, AE El Zowalaty, VI Sayin… - Nature Cancer, 2024 - nature.com
… cells maintain a steady-state redox balance via robust upregulation of cellular antioxidant …
well-tolerated GCL inhibitor used to treat recurrent neuroblastoma 159 and multiple myeloma …
well-tolerated GCL inhibitor used to treat recurrent neuroblastoma 159 and multiple myeloma …
[HTML][HTML] Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation
A Ugun-Klusek, TS Theodosi, JC Fitzgerald, F Burté… - Redox Biology, 2019 - Elsevier
… deamination and contribute to reactive oxygen species (ROS) generation … In neuronal cells,
ETC complex inhibition and other stressors … Steady state levels of autophagy substrate p62 (…
ETC complex inhibition and other stressors … Steady state levels of autophagy substrate p62 (…
[HTML][HTML] Olive Oil Components as Novel Antioxidants in Neuroblastoma Treatment: Exploring the Therapeutic Potential of Oleuropein and Hydroxytyrosol
M Gonçalves, A Aiello, M Rodríguez-Pérez, G Accardi… - Nutrients, 2024 - mdpi.com
… cells produce increased amounts of reactive oxygen species, this review highlights the
antioxidant … These polyphenols might inhibit cell proliferation in a concentration-dependent …
antioxidant … These polyphenols might inhibit cell proliferation in a concentration-dependent …
… overload, mitochondrial damage and cell death due to toxically high doses of dexamethasone-induced oxidative stress in human neuroblastoma SH-SY5Y cells
W Suwanjang, AY Abramov, K Charngkaew… - Neurochemistry …, 2016 - Elsevier
… levels lead to increases in reactive oxygen species (ROS) … for 40 min or until a steady state
had been reached before images … inhibitor NDGA (10 μM) and xanthine oxidase inhibitor …
had been reached before images … inhibitor NDGA (10 μM) and xanthine oxidase inhibitor …
The antioxidants esculetin and quercetin modulate differently redox balance in human NB4 leukemia cells
V Rubio, AI Garcia-Perez, A Herraez, L Puebla… - bioRxiv, 2024 - biorxiv.org
… cell line has increased reactive oxygen species (ROS) levels. Esculetin and quercetin are
antioxidants that alter redox equilibrium, diminishing cell … cell lines, esculetin inhibits cell cycle …
antioxidants that alter redox equilibrium, diminishing cell … cell lines, esculetin inhibits cell cycle …
[HTML][HTML] Hydroxybenzoic acid derivatives as dual-target ligands: mitochondriotropic antioxidants and cholinesterase inhibitors
C Oliveira, F Cagide, J Teixeira, R Amorim… - Frontiers in …, 2018 - frontiersin.org
… observed in differentiated human neuroblastoma (SH-SY5Y) … , high level of potent reactive
oxygen species (ROS), and … , which is the ratio of the steady-state concentrations of the drug in …
oxygen species (ROS), and … , which is the ratio of the steady-state concentrations of the drug in …
[HTML][HTML] Hypoxia induced hERG trafficking defect linked to cell cycle arrest in SH-SY5Y cells
DR Vaddi, L Piao, SA Khan, N Wang, NR Prabhakar… - PloS one, 2019 - journals.plos.org
… In contrast, 2 and 4 days of CH increased the steady state … We previously reported that
reactive oxygen species (ROS) … channels reduce cell proliferation of neuroblastoma cells [16, …
reactive oxygen species (ROS) … channels reduce cell proliferation of neuroblastoma cells [16, …
Reactive oxygen species–mediated synergism of fenretinide and romidepsin in preclinical models of T-cell lymphoid malignancies
… 23), while (due to dosing limitations with mice) the maximum steady state plasma … in
neuroblastoma preclinical models between fenretinide and the microtubule inhibitor ABT-…
neuroblastoma preclinical models between fenretinide and the microtubule inhibitor ABT-…
[HTML][HTML] The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells
J Mett, U Müller - Scientific Reports, 2021 - nature.com
… elevated levels of reactive oxygen and nitrogen species (ROS… the medium and to inhibit cell
proliferation, the concentration … and Neuro2a cells resulting in a declined steady state level …
proliferation, the concentration … and Neuro2a cells resulting in a declined steady state level …
Crosstalk between calcium and reactive oxygen species signaling in cancer
… The interplay between Ca 2+ and reactive oxygen species (ROS) signaling pathways is well
established, with reciprocal regulation occurring at a number of subcellular locations. Many …
established, with reciprocal regulation occurring at a number of subcellular locations. Many …